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Atomistry » Zinc » PDB 5sj8-5skb » 5sj8 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Zinc » PDB 5sj8-5skb » 5sj8 » |
Zinc in PDB 5sj8: Crystal Structure of Human Phosphodiesterase 10 in Complex with 12- Methoxy-5-Methyl-3-Propyl-2,4,8,13-Tetrazatricyclo[7.4.0.02, 6]Trideca-1(13),3,5,7,9,11-Hexaene-7-CarbonitrileEnzymatic activity of Crystal Structure of Human Phosphodiesterase 10 in Complex with 12- Methoxy-5-Methyl-3-Propyl-2,4,8,13-Tetrazatricyclo[7.4.0.02, 6]Trideca-1(13),3,5,7,9,11-Hexaene-7-Carbonitrile
All present enzymatic activity of Crystal Structure of Human Phosphodiesterase 10 in Complex with 12- Methoxy-5-Methyl-3-Propyl-2,4,8,13-Tetrazatricyclo[7.4.0.02, 6]Trideca-1(13),3,5,7,9,11-Hexaene-7-Carbonitrile:
3.1.4.17; Protein crystallography data
The structure of Crystal Structure of Human Phosphodiesterase 10 in Complex with 12- Methoxy-5-Methyl-3-Propyl-2,4,8,13-Tetrazatricyclo[7.4.0.02, 6]Trideca-1(13),3,5,7,9,11-Hexaene-7-Carbonitrile, PDB code: 5sj8
was solved by
C.Joseph,
J.Benz,
A.Flohr,
M.G.Rudolph,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5sj8:
The structure of Crystal Structure of Human Phosphodiesterase 10 in Complex with 12- Methoxy-5-Methyl-3-Propyl-2,4,8,13-Tetrazatricyclo[7.4.0.02, 6]Trideca-1(13),3,5,7,9,11-Hexaene-7-Carbonitrile also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Crystal Structure of Human Phosphodiesterase 10 in Complex with 12- Methoxy-5-Methyl-3-Propyl-2,4,8,13-Tetrazatricyclo[7.4.0.02, 6]Trideca-1(13),3,5,7,9,11-Hexaene-7-Carbonitrile
(pdb code 5sj8). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 4 binding sites of Zinc where determined in the Crystal Structure of Human Phosphodiesterase 10 in Complex with 12- Methoxy-5-Methyl-3-Propyl-2,4,8,13-Tetrazatricyclo[7.4.0.02, 6]Trideca-1(13),3,5,7,9,11-Hexaene-7-Carbonitrile, PDB code: 5sj8: Jump to Zinc binding site number: 1; 2; 3; 4; Zinc binding site 1 out of 4 in 5sj8Go back to Zinc Binding Sites List in 5sj8
Zinc binding site 1 out
of 4 in the Crystal Structure of Human Phosphodiesterase 10 in Complex with 12- Methoxy-5-Methyl-3-Propyl-2,4,8,13-Tetrazatricyclo[7.4.0.02, 6]Trideca-1(13),3,5,7,9,11-Hexaene-7-Carbonitrile
Mono view Stereo pair view
Zinc binding site 2 out of 4 in 5sj8Go back to Zinc Binding Sites List in 5sj8
Zinc binding site 2 out
of 4 in the Crystal Structure of Human Phosphodiesterase 10 in Complex with 12- Methoxy-5-Methyl-3-Propyl-2,4,8,13-Tetrazatricyclo[7.4.0.02, 6]Trideca-1(13),3,5,7,9,11-Hexaene-7-Carbonitrile
Mono view Stereo pair view
Zinc binding site 3 out of 4 in 5sj8Go back to Zinc Binding Sites List in 5sj8
Zinc binding site 3 out
of 4 in the Crystal Structure of Human Phosphodiesterase 10 in Complex with 12- Methoxy-5-Methyl-3-Propyl-2,4,8,13-Tetrazatricyclo[7.4.0.02, 6]Trideca-1(13),3,5,7,9,11-Hexaene-7-Carbonitrile
Mono view Stereo pair view
Zinc binding site 4 out of 4 in 5sj8Go back to Zinc Binding Sites List in 5sj8
Zinc binding site 4 out
of 4 in the Crystal Structure of Human Phosphodiesterase 10 in Complex with 12- Methoxy-5-Methyl-3-Propyl-2,4,8,13-Tetrazatricyclo[7.4.0.02, 6]Trideca-1(13),3,5,7,9,11-Hexaene-7-Carbonitrile
Mono view Stereo pair view
Reference:
A.Flohr,
D.Schlatter,
B.Kuhn,
M.G.Rudolph.
Crystal Structure of A Human Phosphodiesterase 10 Complex To Be Published.
Page generated: Mon Oct 28 05:58:45 2024
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