Zinc in PDB 5r4u: Pandda Analysis Group Deposition -- Crystal Structure of Human Cleavage Factor Im in Complex with EN08775-43

The structure of Pandda Analysis Group Deposition -- Crystal Structure of Human Cleavage Factor Im in Complex with EN08775-43, PDB code: 5r4u was solved by S.L.Kidd, N.Mateu, R.Talon, T.Krojer, A.Aimon, A.R.Bradley, M.Fairhead, L.Diaz-Saez, H.F.Sore, A.Madin, K.V.M.Huber, F.Von Delft, D.R.Spring, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	49.78 / 1.92
Space group	P 32 2 1
Cell size a, b, c (Å), α, β, γ (°)	59.060, 59.060, 212.700, 90.00, 90.00, 120.00
R / Rfree (%)	21.4 / 26.6

The binding sites of Zinc atom in the Pandda Analysis Group Deposition -- Crystal Structure of Human Cleavage Factor Im in Complex with EN08775-43 (pdb code 5r4u). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 6 binding sites of Zinc where determined in the Pandda Analysis Group Deposition -- Crystal Structure of Human Cleavage Factor Im in Complex with EN08775-43, PDB code: 5r4u:
Jump to Zinc binding site number: 1; 2; 3; 4; 5; 6;

Zinc binding site 1 out of 6 in the Pandda Analysis Group Deposition -- Crystal Structure of Human Cleavage Factor Im in Complex with EN08775-43


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Pandda Analysis Group Deposition -- Crystal Structure of Human Cleavage Factor Im in Complex with EN08775-43 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn302 b:0.1 occ:1.00 NE1 A:TRP149 2.9 30.9 1.0 O A:HOH524 2.9 42.8 1.0 ND1 A:HIS171 3.5 28.4 1.0 CE A:MET76 3.5 25.5 1.0 CE2 A:TRP149 3.7 29.0 1.0 CG A:HIS171 3.8 24.6 1.0 CZ2 A:TRP149 3.9 31.6 1.0 CD1 A:TRP149 4.0 26.6 1.0 CB A:HIS171 4.0 22.6 1.0 CE1 A:HIS171 4.1 27.3 1.0 SD A:MET76 4.1 27.1 1.0 CD2 A:HIS171 4.5 24.6 1.0 O A:HOH462 4.5 47.7 1.0 NE2 A:HIS171 4.7 24.2 1.0 CD1 A:ILE161 4.8 39.8 1.0

Zinc binding site 2 out of 6 in the Pandda Analysis Group Deposition -- Crystal Structure of Human Cleavage Factor Im in Complex with EN08775-43


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Pandda Analysis Group Deposition -- Crystal Structure of Human Cleavage Factor Im in Complex with EN08775-43 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn303 b:1.0 occ:1.00 ND1 A:HIS89 2.8 28.1 1.0 CA A:HIS89 3.3 30.9 1.0 CB A:HIS89 3.6 29.8 1.0 CG A:HIS89 3.6 28.1 1.0 CE1 A:HIS89 3.9 28.6 1.0 N A:HIS89 4.1 27.4 1.0 C A:HIS89 4.2 32.2 1.0 O A:HOH490 4.3 35.4 1.0 O A:HIS89 4.8 32.6 1.0 N A:ARG90 4.8 32.1 1.0 CD2 A:HIS89 4.9 23.5 1.0 NE2 A:HIS89 5.0 24.3 1.0

Zinc binding site 3 out of 6 in the Pandda Analysis Group Deposition -- Crystal Structure of Human Cleavage Factor Im in Complex with EN08775-43


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Pandda Analysis Group Deposition -- Crystal Structure of Human Cleavage Factor Im in Complex with EN08775-43 within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn301 b:30.1 occ:1.00 O B:HOH401 1.8 24.3 1.0 OE1 B:GLU88 1.9 34.6 0.3 O B:HOH439 2.0 18.7 1.0 NE2 B:HIS93 2.2 25.4 1.0 CD B:GLU88 2.8 35.6 0.3 CD2 B:HIS93 3.0 22.6 1.0 CE1 B:HIS93 3.2 24.3 1.0 CG B:GLU88 3.3 34.5 0.3 OE2 B:GLU88 3.8 37.6 0.3 CB B:GLU88 4.2 31.6 0.2 CG B:HIS93 4.2 22.2 1.0 ND1 B:HIS93 4.3 23.0 1.0 CG B:GLU88 4.3 32.3 0.2 O B:GLU88 4.5 39.5 0.3 CG B:PRO197 4.6 25.9 1.0 CB B:PRO197 4.6 26.3 1.0 CD B:PRO197 4.7 24.9 1.0 CB B:GLU88 4.8 33.9 0.3 ND1 B:HIS89 5.0 41.2 0.3

Zinc binding site 4 out of 6 in the Pandda Analysis Group Deposition -- Crystal Structure of Human Cleavage Factor Im in Complex with EN08775-43


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Pandda Analysis Group Deposition -- Crystal Structure of Human Cleavage Factor Im in Complex with EN08775-43 within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn302 b:38.2 occ:1.00 NE2 B:HIS164 1.7 26.2 1.0 O B:HOH488 2.6 34.3 1.0 CE1 B:HIS164 2.6 29.8 1.0 CD2 B:HIS164 2.9 29.2 1.0 ND1 B:HIS164 3.7 28.9 1.0 CG B:HIS164 3.9 28.2 1.0

Zinc binding site 5 out of 6 in the Pandda Analysis Group Deposition -- Crystal Structure of Human Cleavage Factor Im in Complex with EN08775-43


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 5 of Pandda Analysis Group Deposition -- Crystal Structure of Human Cleavage Factor Im in Complex with EN08775-43 within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn303 b:0.1 occ:1.00 O B:HOH461 3.8 48.3 1.0 ND1 B:HIS164 4.1 28.9 1.0 CE1 B:HIS164 4.2 29.8 1.0

Zinc binding site 6 out of 6 in the Pandda Analysis Group Deposition -- Crystal Structure of Human Cleavage Factor Im in Complex with EN08775-43


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 6 of Pandda Analysis Group Deposition -- Crystal Structure of Human Cleavage Factor Im in Complex with EN08775-43 within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn304 b:0.5 occ:1.00 NE1 B:TRP149 2.9 32.1 1.0 CD1 B:TRP149 3.6 30.2 1.0 CD1 B:ILE161 3.8 37.0 1.0 CE2 B:TRP149 3.8 32.2 1.0 CE B:MET76 4.2 35.4 1.0 SD B:MET76 4.3 33.7 1.0 CZ2 B:TRP149 4.3 35.3 1.0 CG B:PRO168 4.4 32.5 1.0 CG1 B:ILE161 4.6 34.3 1.0 ND1 B:HIS171 4.6 28.1 1.0 CG B:TRP149 4.8 29.2 1.0 CG B:HIS171 4.8 25.5 1.0 CB B:HIS171 4.8 22.4 1.0 CD2 B:TRP149 4.9 29.7 1.0

S.L.Kidd, N.Mateu, R.Talon, T.Krojer, A.Aimon, A.R.Bradley, M.Fairhead, L.Diaz-Saez, H.F.Sore, A.Madin, K.V.M.Huber, F.Von Delft, D.R.Spring. Pandda Analysis Group Deposition To Be Published.