Zinc in PDB 5r4q: Pandda Analysis Group Deposition -- Crystal Structure of Human Cleavage Factor Im in Complex with NM466-1

The structure of Pandda Analysis Group Deposition -- Crystal Structure of Human Cleavage Factor Im in Complex with NM466-1, PDB code: 5r4q was solved by S.L.Kidd, N.Mateu, R.Talon, T.Krojer, A.Aimon, A.R.Bradley, M.Fairhead, L.Diaz-Saez, H.F.Sore, A.Madin, K.V.M.Huber, F.Von Delft, D.R.Spring, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	71.48 / 1.49
Space group	P 32 2 1
Cell size a, b, c (Å), α, β, γ (°)	59.680, 59.680, 214.430, 90.00, 90.00, 120.00
R / Rfree (%)	21.8 / 25

The binding sites of Zinc atom in the Pandda Analysis Group Deposition -- Crystal Structure of Human Cleavage Factor Im in Complex with NM466-1 (pdb code 5r4q). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 6 binding sites of Zinc where determined in the Pandda Analysis Group Deposition -- Crystal Structure of Human Cleavage Factor Im in Complex with NM466-1, PDB code: 5r4q:
Jump to Zinc binding site number: 1; 2; 3; 4; 5; 6;

Zinc binding site 1 out of 6 in the Pandda Analysis Group Deposition -- Crystal Structure of Human Cleavage Factor Im in Complex with NM466-1


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Pandda Analysis Group Deposition -- Crystal Structure of Human Cleavage Factor Im in Complex with NM466-1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn301 b:0.1 occ:1.00 NE1 A:TRP149 2.6 39.7 1.0 ND1 A:HIS171 3.1 29.3 1.0 CG A:HIS171 3.3 22.4 1.0 O A:HOH535 3.3 53.6 1.0 CE2 A:TRP149 3.5 30.7 1.0 CB A:HIS171 3.6 21.3 1.0 CE A:MET76 3.6 29.4 1.0 CD1 A:TRP149 3.6 31.1 1.0 CE1 A:HIS171 3.7 30.1 1.0 CZ2 A:TRP149 3.7 36.1 1.0 CD2 A:HIS171 4.0 23.3 1.0 SD A:MET76 4.0 28.9 1.0 O A:HOH419 4.2 32.9 1.0 NE2 A:HIS171 4.2 27.1 1.0 CD2 A:TRP149 4.7 33.8 1.0 CG A:TRP149 4.8 26.5 1.0 CA A:HIS171 4.8 21.7 1.0 CD1 A:ILE161 4.9 38.3 1.0

Zinc binding site 2 out of 6 in the Pandda Analysis Group Deposition -- Crystal Structure of Human Cleavage Factor Im in Complex with NM466-1


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Pandda Analysis Group Deposition -- Crystal Structure of Human Cleavage Factor Im in Complex with NM466-1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn302 b:0.8 occ:1.00 ND1 A:HIS89 2.3 30.6 1.0 CG A:HIS89 3.2 29.5 1.0 CE1 A:HIS89 3.3 29.7 1.0 CB A:HIS89 3.4 30.4 1.0 CA A:HIS89 3.4 31.0 1.0 N A:HIS89 4.3 29.2 1.0 CD2 A:HIS89 4.4 28.4 1.0 O A:HOH470 4.4 45.0 1.0 NE2 A:HIS89 4.4 27.8 1.0 C A:HIS89 4.5 32.9 1.0

Zinc binding site 3 out of 6 in the Pandda Analysis Group Deposition -- Crystal Structure of Human Cleavage Factor Im in Complex with NM466-1


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Pandda Analysis Group Deposition -- Crystal Structure of Human Cleavage Factor Im in Complex with NM466-1 within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn301 b:31.7 occ:1.00 O B:HOH401 1.0 15.6 1.0 NE2 B:HIS93 2.0 22.7 1.0 OE1 B:GLU88 2.1 35.5 0.5 CE1 B:HIS93 2.8 26.6 1.0 CD B:GLU88 3.0 40.5 0.5 CD2 B:HIS93 3.2 25.9 1.0 CG B:GLU88 3.2 40.0 0.5 ND1 B:HIS93 4.0 25.1 1.0 OE2 B:GLU88 4.2 40.8 0.5 CG B:HIS93 4.2 24.2 1.0 O B:GLU88 4.3 41.6 0.5 CG B:PRO197 4.5 28.9 1.0 CB B:PRO197 4.6 29.0 1.0 ND1 B:HIS89 4.7 54.0 0.5 CB B:GLU88 4.7 39.2 0.5 CD B:PRO197 4.8 26.7 1.0

Zinc binding site 4 out of 6 in the Pandda Analysis Group Deposition -- Crystal Structure of Human Cleavage Factor Im in Complex with NM466-1


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Pandda Analysis Group Deposition -- Crystal Structure of Human Cleavage Factor Im in Complex with NM466-1 within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn302 b:38.1 occ:1.00 NE2 B:HIS164 1.9 40.4 1.0 CD2 B:HIS164 2.9 31.8 1.0 CE1 B:HIS164 2.9 35.1 1.0 ND1 B:HIS164 4.0 33.5 1.0 CG B:HIS164 4.0 31.6 1.0

Zinc binding site 5 out of 6 in the Pandda Analysis Group Deposition -- Crystal Structure of Human Cleavage Factor Im in Complex with NM466-1


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 5 of Pandda Analysis Group Deposition -- Crystal Structure of Human Cleavage Factor Im in Complex with NM466-1 within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn303 b:0.6 occ:1.00 ND1 B:HIS164 3.9 33.5 1.0 CE1 B:HIS164 4.2 35.1 1.0 CG B:HIS164 5.0 31.6 1.0

Zinc binding site 6 out of 6 in the Pandda Analysis Group Deposition -- Crystal Structure of Human Cleavage Factor Im in Complex with NM466-1


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 6 of Pandda Analysis Group Deposition -- Crystal Structure of Human Cleavage Factor Im in Complex with NM466-1 within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn304 b:0.4 occ:1.00 NE1 B:TRP149 2.3 38.3 1.0 CE2 B:TRP149 3.2 32.7 1.0 CD1 B:TRP149 3.3 36.7 1.0 ND1 B:HIS171 3.5 32.5 1.0 CZ2 B:TRP149 3.6 38.8 1.0 CG B:HIS171 3.7 28.0 1.0 CE1 B:HIS171 3.9 33.1 1.0 CB B:HIS171 4.1 27.2 1.0 CD2 B:HIS171 4.2 29.7 1.0 CE B:MET76 4.2 35.9 1.0 CD1 B:ILE161 4.3 43.1 1.0 NE2 B:HIS171 4.4 32.2 1.0 SD B:MET76 4.4 35.8 1.0 CD2 B:TRP149 4.5 35.7 1.0 CG B:TRP149 4.5 34.0 1.0 CG1 B:ILE161 4.9 38.8 1.0 CH2 B:TRP149 5.0 39.6 1.0

S.L.Kidd, N.Mateu, R.Talon, T.Krojer, A.Aimon, A.R.Bradley, M.Fairhead, L.Diaz-Saez, H.F.Sore, A.Madin, K.V.M.Huber, F.Von Delft, D.R.Spring. Pandda Analysis Group Deposition To Be Published.