Zinc in PDB 5oj7: Sirtuin 4 Orthologue From Xenopus Tropicalis in Complex with Adp- Ribose

The structure of Sirtuin 4 Orthologue From Xenopus Tropicalis in Complex with Adp- Ribose, PDB code: 5oj7 was solved by M.Pannek, C.Steegborn, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	19.73 / 1.58
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	69.390, 74.660, 109.700, 90.00, 90.00, 90.00
R / Rfree (%)	15.2 / 18.6

The binding sites of Zinc atom in the Sirtuin 4 Orthologue From Xenopus Tropicalis in Complex with Adp- Ribose (pdb code 5oj7). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Sirtuin 4 Orthologue From Xenopus Tropicalis in Complex with Adp- Ribose, PDB code: 5oj7:

Zinc binding site 1 out of 1 in the Sirtuin 4 Orthologue From Xenopus Tropicalis in Complex with Adp- Ribose


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Sirtuin 4 Orthologue From Xenopus Tropicalis in Complex with Adp- Ribose within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn402 b:26.2 occ:1.00 SG A:CYS171 2.3 25.7 1.0 SG A:CYS219 2.3 24.9 1.0 SG A:CYS222 2.3 27.7 1.0 SG A:CYS168 2.3 23.8 1.0 CB A:CYS219 3.1 23.7 1.0 CB A:CYS168 3.3 23.6 1.0 CB A:CYS171 3.3 28.7 1.0 CB A:CYS222 3.4 27.0 1.0 N A:CYS171 3.7 26.7 1.0 N A:CYS222 3.9 27.7 1.0 CA A:CYS171 4.0 28.9 1.0 CA A:CYS222 4.1 26.2 1.0 N A:GLY224 4.4 25.7 1.0 C A:GLY170 4.5 31.9 1.0 CB A:LYS221 4.5 34.8 1.0 CA A:CYS219 4.6 22.1 1.0 CA A:CYS168 4.7 23.3 1.0 C A:CYS222 4.7 28.3 1.0 CA A:GLY170 4.7 28.8 1.0 N A:GLY223 4.7 26.3 1.0 CA A:GLY224 4.8 26.7 1.0 C A:LYS221 4.8 31.6 1.0 O A:HOH737 4.8 26.6 1.0 C A:CYS171 4.8 27.5 1.0 N A:GLY170 4.9 27.8 1.0 OG1 A:THR173 4.9 29.8 1.0

M.Pannek, Z.Simic, M.Fuszard, M.Meleshin, D.Rotili, A.Mai, M.Schutkowski, C.Steegborn. Crystal Structures of the Mitochondrial Deacylase Sirtuin 4 Reveal Isoform-Specific Acyl Recognition and Regulation Features. Nat Commun V. 8 1513 2017.
ISSN: ESSN 2041-1723
PubMed: 29138502
DOI: 10.1038/S41467-017-01701-2