|
Atomistry » Zinc » PDB 5nse-5o1i » 5o1i | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Zinc » PDB 5nse-5o1i » 5o1i » |
Zinc in PDB 5o1i: P53 Cancer Mutant Y220C in Complex with Compound MB710Protein crystallography data
The structure of P53 Cancer Mutant Y220C in Complex with Compound MB710, PDB code: 5o1i
was solved by
A.C.Joerger,
M.G.J.Baud,
M.R.Bauer,
A.R.Fersht,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5o1i:
The structure of P53 Cancer Mutant Y220C in Complex with Compound MB710 also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the P53 Cancer Mutant Y220C in Complex with Compound MB710
(pdb code 5o1i). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the P53 Cancer Mutant Y220C in Complex with Compound MB710, PDB code: 5o1i: Jump to Zinc binding site number: 1; 2; Zinc binding site 1 out of 2 in 5o1iGo back to Zinc Binding Sites List in 5o1i
Zinc binding site 1 out
of 2 in the P53 Cancer Mutant Y220C in Complex with Compound MB710
Mono view Stereo pair view
Zinc binding site 2 out of 2 in 5o1iGo back to Zinc Binding Sites List in 5o1i
Zinc binding site 2 out
of 2 in the P53 Cancer Mutant Y220C in Complex with Compound MB710
Mono view Stereo pair view
Reference:
M.G.J.Baud,
M.R.Bauer,
L.Verduci,
F.A.Dingler,
K.J.Patel,
D.Horil Roy,
A.C.Joerger,
A.R.Fersht.
Aminobenzothiazole Derivatives Stabilize the Thermolabile P53 Cancer Mutant Y220C and Show Anticancer Activity in P53-Y220C Cell Lines. Eur J Med Chem V. 152 101 2018.
Page generated: Sun Oct 27 23:12:32 2024
ISSN: ISSN 1768-3254 PubMed: 29702446 DOI: 10.1016/J.EJMECH.2018.04.035 |
Last articlesZn in 9JYWZn in 9IR4 Zn in 9IR3 Zn in 9GMX Zn in 9GMW Zn in 9JEJ Zn in 9ERF Zn in 9ERE Zn in 9EGV Zn in 9EGW |
© Copyright 2008-2020 by atomistry.com | ||
Home | Site Map | Copyright | Contact us | Privacy |