Zinc in PDB 5mey: Crystal Structure of SMAD4-MH1 Bound to the Ggcgc Site.

The structure of Crystal Structure of SMAD4-MH1 Bound to the Ggcgc Site., PDB code: 5mey was solved by Z.Kaczmarska, R.Freier, J.A.Marquez, M.J.Macias, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.70 / 2.05
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	64.170, 79.000, 90.100, 90.00, 90.00, 90.00
R / Rfree (%)	22.2 / 23.8

The structure of Crystal Structure of SMAD4-MH1 Bound to the Ggcgc Site. also contains other interesting chemical elements:

Calcium	(Ca)	5 atoms
Chlorine	(Cl)	4 atoms

The binding sites of Zinc atom in the Crystal Structure of SMAD4-MH1 Bound to the Ggcgc Site. (pdb code 5mey). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of SMAD4-MH1 Bound to the Ggcgc Site., PDB code: 5mey:

Zinc binding site 1 out of 1 in the Crystal Structure of SMAD4-MH1 Bound to the Ggcgc Site.


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of SMAD4-MH1 Bound to the Ggcgc Site. within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn201 b:45.8 occ:1.00 SG A:CYS115 2.1 51.1 1.0 ND1 A:HIS132 2.1 50.0 1.0 SG A:CYS127 2.5 39.3 1.0 SG A:CYS71 2.5 53.2 1.0 CB A:CYS127 3.0 35.3 1.0 CE1 A:HIS132 3.1 49.3 1.0 CG A:HIS132 3.1 48.0 1.0 CB A:CYS115 3.2 48.0 1.0 CB A:HIS132 3.4 44.0 1.0 CB A:CYS71 3.5 48.8 1.0 CA A:CYS115 3.7 48.6 1.0 CA A:CYS71 3.8 47.9 1.0 NE2 A:HIS132 4.2 49.6 1.0 CD2 A:HIS132 4.2 49.7 1.0 C A:CYS115 4.4 50.0 1.0 N A:GLN116 4.4 46.2 1.0 N A:CYS71 4.5 49.3 1.0 CA A:CYS127 4.5 34.4 1.0 N A:TYR117 4.6 47.4 1.0 N A:ALA118 4.8 44.1 1.0 CA A:HIS132 4.9 42.4 1.0 CB A:ASN129 5.0 39.2 1.0 C A:CYS71 5.0 47.1 1.0 N A:VAL72 5.0 41.0 1.0 N A:CYS115 5.0 50.8 1.0

P.Martin-Malpartida, M.Batet, Z.Kaczmarska, R.Freier, T.Gomes, E.Aragon, Y.Zou, Q.Wang, Q.Xi, L.Ruiz, A.Vea, J.A.Marquez, J.Massague, M.J.Macias. Structural Basis For Genome Wide Recognition of 5-Bp Gc Motifs By Smad Transcription Factors. Nat Commun V. 8 2070 2017.
ISSN: ESSN 2041-1723
PubMed: 29234012
DOI: 10.1038/S41467-017-02054-6