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Atomistry » Zinc » PDB 5lsx-5m2h » 5m0d | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Zinc » PDB 5lsx-5m2h » 5m0d » |
Zinc in PDB 5m0d: Structure-Based Evolution of A Hybrid Steroid Series of Autotaxin InhibitorsEnzymatic activity of Structure-Based Evolution of A Hybrid Steroid Series of Autotaxin Inhibitors
All present enzymatic activity of Structure-Based Evolution of A Hybrid Steroid Series of Autotaxin Inhibitors:
3.1.4.39; Protein crystallography data
The structure of Structure-Based Evolution of A Hybrid Steroid Series of Autotaxin Inhibitors, PDB code: 5m0d
was solved by
W.-J.Keune,
T.Heidebrecht,
A.Perrakis,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5m0d:
The structure of Structure-Based Evolution of A Hybrid Steroid Series of Autotaxin Inhibitors also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Structure-Based Evolution of A Hybrid Steroid Series of Autotaxin Inhibitors
(pdb code 5m0d). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Structure-Based Evolution of A Hybrid Steroid Series of Autotaxin Inhibitors, PDB code: 5m0d: Jump to Zinc binding site number: 1; 2; Zinc binding site 1 out of 2 in 5m0dGo back to Zinc Binding Sites List in 5m0d
Zinc binding site 1 out
of 2 in the Structure-Based Evolution of A Hybrid Steroid Series of Autotaxin Inhibitors
Mono view Stereo pair view
Zinc binding site 2 out of 2 in 5m0dGo back to Zinc Binding Sites List in 5m0d
Zinc binding site 2 out
of 2 in the Structure-Based Evolution of A Hybrid Steroid Series of Autotaxin Inhibitors
Mono view Stereo pair view
Reference:
W.J.Keune,
F.Potjewyd,
T.Heidebrecht,
F.Salgado-Polo,
S.J.Macdonald,
L.Chelvarajan,
A.Abdel Latif,
S.Soman,
A.J.Morris,
A.J.Watson,
C.Jamieson,
A.Perrakis.
Rational Design of Autotaxin Inhibitors By Structural Evolution of Endogenous Modulators. J. Med. Chem. V. 60 2006 2017.
Page generated: Sun Oct 27 21:35:52 2024
ISSN: ISSN 1520-4804 PubMed: 28165241 DOI: 10.1021/ACS.JMEDCHEM.6B01743 |
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