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Atomistry » Zinc » PDB 5ijs-5j0e » 5ipz | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Zinc » PDB 5ijs-5j0e » 5ipz » |
Zinc in PDB 5ipz: Crystal Structure of Human Carbonic Anhydrase Isozyme IV with 5-(2- Amino-1,3-Thiazol-4-Yl)-2-ChlorobenzenesulfonamideEnzymatic activity of Crystal Structure of Human Carbonic Anhydrase Isozyme IV with 5-(2- Amino-1,3-Thiazol-4-Yl)-2-Chlorobenzenesulfonamide
All present enzymatic activity of Crystal Structure of Human Carbonic Anhydrase Isozyme IV with 5-(2- Amino-1,3-Thiazol-4-Yl)-2-Chlorobenzenesulfonamide:
4.2.1.1; Protein crystallography data
The structure of Crystal Structure of Human Carbonic Anhydrase Isozyme IV with 5-(2- Amino-1,3-Thiazol-4-Yl)-2-Chlorobenzenesulfonamide, PDB code: 5ipz
was solved by
A.Smirnov,
E.Manakova,
S.Grazulis,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5ipz:
The structure of Crystal Structure of Human Carbonic Anhydrase Isozyme IV with 5-(2- Amino-1,3-Thiazol-4-Yl)-2-Chlorobenzenesulfonamide also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Crystal Structure of Human Carbonic Anhydrase Isozyme IV with 5-(2- Amino-1,3-Thiazol-4-Yl)-2-Chlorobenzenesulfonamide
(pdb code 5ipz). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 4 binding sites of Zinc where determined in the Crystal Structure of Human Carbonic Anhydrase Isozyme IV with 5-(2- Amino-1,3-Thiazol-4-Yl)-2-Chlorobenzenesulfonamide, PDB code: 5ipz: Jump to Zinc binding site number: 1; 2; 3; 4; Zinc binding site 1 out of 4 in 5ipzGo back to Zinc Binding Sites List in 5ipz
Zinc binding site 1 out
of 4 in the Crystal Structure of Human Carbonic Anhydrase Isozyme IV with 5-(2- Amino-1,3-Thiazol-4-Yl)-2-Chlorobenzenesulfonamide
Mono view Stereo pair view
Zinc binding site 2 out of 4 in 5ipzGo back to Zinc Binding Sites List in 5ipz
Zinc binding site 2 out
of 4 in the Crystal Structure of Human Carbonic Anhydrase Isozyme IV with 5-(2- Amino-1,3-Thiazol-4-Yl)-2-Chlorobenzenesulfonamide
Mono view Stereo pair view
Zinc binding site 3 out of 4 in 5ipzGo back to Zinc Binding Sites List in 5ipz
Zinc binding site 3 out
of 4 in the Crystal Structure of Human Carbonic Anhydrase Isozyme IV with 5-(2- Amino-1,3-Thiazol-4-Yl)-2-Chlorobenzenesulfonamide
Mono view Stereo pair view
Zinc binding site 4 out of 4 in 5ipzGo back to Zinc Binding Sites List in 5ipz
Zinc binding site 4 out
of 4 in the Crystal Structure of Human Carbonic Anhydrase Isozyme IV with 5-(2- Amino-1,3-Thiazol-4-Yl)-2-Chlorobenzenesulfonamide
Mono view Stereo pair view
Reference:
A.Mickeviciute,
D.D.Timm,
M.Gedgaudas,
V.Linkuviene,
Z.Chen,
A.Waheed,
V.Michailoviene,
A.Zubriene,
A.Smirnov,
E.Capkauskaite,
L.Baranauskiene,
J.Jachno,
J.Revuckiene,
E.Manakova,
S.Grazulis,
J.Matuliene,
E.Di Cera,
W.S.Sly,
D.Matulis.
Intrinsic Thermodynamics of High Affinity Inhibitor Binding to Recombinant Human Carbonic Anhydrase IV. Eur. Biophys. J. V. 47 271 2018.
Page generated: Sun Oct 27 18:19:33 2024
ISSN: ISSN 1432-1017 PubMed: 28975383 DOI: 10.1007/S00249-017-1256-0 |
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