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Atomistry » Zinc » PDB 5hou-5i3a » 5i02 » |
Zinc in PDB 5i02: Trna Guanine Transglycosylase (Tgt) in Co-Crystallized Complex with 6- Amino-4-{2-[(Cyclohexylmethyl)Amino]Ethyl}-2-(Methylamino)-1,7- Dihydro-8H-Imidazo[4,5-G]Quinazolin-8-OneEnzymatic activity of Trna Guanine Transglycosylase (Tgt) in Co-Crystallized Complex with 6- Amino-4-{2-[(Cyclohexylmethyl)Amino]Ethyl}-2-(Methylamino)-1,7- Dihydro-8H-Imidazo[4,5-G]Quinazolin-8-One
All present enzymatic activity of Trna Guanine Transglycosylase (Tgt) in Co-Crystallized Complex with 6- Amino-4-{2-[(Cyclohexylmethyl)Amino]Ethyl}-2-(Methylamino)-1,7- Dihydro-8H-Imidazo[4,5-G]Quinazolin-8-One:
2.4.2.29; Protein crystallography data
The structure of Trna Guanine Transglycosylase (Tgt) in Co-Crystallized Complex with 6- Amino-4-{2-[(Cyclohexylmethyl)Amino]Ethyl}-2-(Methylamino)-1,7- Dihydro-8H-Imidazo[4,5-G]Quinazolin-8-One, PDB code: 5i02
was solved by
F.R.Ehrmann,
D.Nguyen,
A.Heine,
G.Klebe,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5i02:
The structure of Trna Guanine Transglycosylase (Tgt) in Co-Crystallized Complex with 6- Amino-4-{2-[(Cyclohexylmethyl)Amino]Ethyl}-2-(Methylamino)-1,7- Dihydro-8H-Imidazo[4,5-G]Quinazolin-8-One also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Trna Guanine Transglycosylase (Tgt) in Co-Crystallized Complex with 6- Amino-4-{2-[(Cyclohexylmethyl)Amino]Ethyl}-2-(Methylamino)-1,7- Dihydro-8H-Imidazo[4,5-G]Quinazolin-8-One
(pdb code 5i02). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Trna Guanine Transglycosylase (Tgt) in Co-Crystallized Complex with 6- Amino-4-{2-[(Cyclohexylmethyl)Amino]Ethyl}-2-(Methylamino)-1,7- Dihydro-8H-Imidazo[4,5-G]Quinazolin-8-One, PDB code: 5i02: Zinc binding site 1 out of 1 in 5i02Go back to![]() ![]()
Zinc binding site 1 out
of 1 in the Trna Guanine Transglycosylase (Tgt) in Co-Crystallized Complex with 6- Amino-4-{2-[(Cyclohexylmethyl)Amino]Ethyl}-2-(Methylamino)-1,7- Dihydro-8H-Imidazo[4,5-G]Quinazolin-8-One
![]() Mono view ![]() Stereo pair view
Reference:
F.R.Ehrmann,
J.Stojko,
A.Heine,
F.Diederich,
K.Reuter,
S.Sanglier-Cianferani,
G.Klebe.
Co-Crystallization, Isothermal Titration Calorimetry and Nanoesi-Ms Reveal Dimer Disturbing Inhibitors To Be Published.
Page generated: Wed Dec 16 06:21:02 2020
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