Zinc in PDB 5g4c: Human SIRT2 Catalyse Short Chain Fatty Acyl Lysine

The structure of Human SIRT2 Catalyse Short Chain Fatty Acyl Lysine, PDB code: 5g4c was solved by Y.Wang, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	40.00 / 2.10
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	37.341, 117.310, 71.346, 90.00, 92.65, 90.00
R / Rfree (%)	18.3 / 22

The binding sites of Zinc atom in the Human SIRT2 Catalyse Short Chain Fatty Acyl Lysine (pdb code 5g4c). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Human SIRT2 Catalyse Short Chain Fatty Acyl Lysine, PDB code: 5g4c:

Zinc binding site 1 out of 1 in the Human SIRT2 Catalyse Short Chain Fatty Acyl Lysine


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Human SIRT2 Catalyse Short Chain Fatty Acyl Lysine within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1356 b:21.6 occ:1.00 SG A:CYS200 2.3 23.1 1.0 SG A:CYS224 2.4 19.2 1.0 SG A:CYS221 2.4 21.4 1.0 SG A:CYS195 2.5 34.4 1.0 CB A:CYS200 3.1 22.3 1.0 CB A:CYS221 3.2 19.1 1.0 CB A:CYS195 3.2 23.0 1.0 CB A:CYS224 3.4 19.5 1.0 N A:CYS224 3.9 25.5 1.0 CB A:HIS202 4.1 20.9 1.0 CA A:CYS224 4.1 25.6 1.0 N A:HIS202 4.4 21.8 1.0 CA A:CYS200 4.5 28.5 1.0 CB A:SER197 4.6 25.8 1.0 N A:ARG201 4.6 22.0 1.0 CA A:CYS221 4.7 25.9 1.0 C A:CYS224 4.7 23.4 1.0 O A:HOH2088 4.7 29.8 1.0 CA A:CYS195 4.7 19.3 1.0 C A:CYS200 4.7 26.1 1.0 CB A:SER226 4.8 18.6 1.0 N A:GLN225 4.8 19.4 1.0 CB A:ASP223 4.8 25.8 1.0 CA A:HIS202 4.9 20.7 1.0 N A:SER226 4.9 21.4 1.0 OG A:SER226 5.0 23.9 1.0

J.Jin, B.He, X.Zhang, H.Lin, Y.Wang. SIRT2 Reverses 4-Oxononanoyl Lysine Modification on Histones. J. Am. Chem. Soc. V. 138 12304 2016.
ISSN: ESSN 1520-5126
PubMed: 27610633
DOI: 10.1021/JACS.6B04977