Zinc in PDB 5g32: Structure of RAD14 in Complex with Acetylaminophenyl-Guanine Containing Dna

The structure of Structure of RAD14 in Complex with Acetylaminophenyl-Guanine Containing Dna, PDB code: 5g32 was solved by N.Simon, C.Ebert, S.Schneider, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	52.96 / 2.20
Space group	P 41
Cell size a, b, c (Å), α, β, γ (°)	52.964, 52.964, 130.945, 90.00, 90.00, 90.00
R / Rfree (%)	21.8 / 26.6

The binding sites of Zinc atom in the Structure of RAD14 in Complex with Acetylaminophenyl-Guanine Containing Dna (pdb code 5g32). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Structure of RAD14 in Complex with Acetylaminophenyl-Guanine Containing Dna, PDB code: 5g32:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Structure of RAD14 in Complex with Acetylaminophenyl-Guanine Containing Dna


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of RAD14 in Complex with Acetylaminophenyl-Guanine Containing Dna within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1302 b:36.5 occ:1.00 SG A:CYS191 2.2 36.9 1.0 SG A:CYS216 2.2 33.3 1.0 SG A:CYS213 2.4 32.6 1.0 SG A:CYS194 2.5 37.5 1.0 CB A:CYS216 3.2 32.5 1.0 CB A:CYS194 3.2 39.0 1.0 CB A:CYS191 3.2 38.3 1.0 CB A:CYS213 3.6 33.2 1.0 N A:CYS194 3.6 40.9 1.0 CA A:CYS194 4.0 41.1 1.0 N A:CYS213 4.1 33.3 1.0 N A:CYS216 4.3 31.8 1.0 CA A:CYS216 4.3 32.6 1.0 CB A:GLU193 4.3 43.7 1.0 CA A:CYS213 4.4 32.9 1.0 CB A:ASN197 4.4 36.3 1.0 C A:GLU193 4.6 43.0 1.0 CA A:CYS191 4.6 39.4 1.0 ND2 A:ASN197 4.6 34.8 1.0 N A:GLU193 4.8 41.9 1.0 CA A:GLU193 4.8 43.2 1.0 O A:CYS213 4.9 30.1 1.0 C A:CYS194 5.0 42.4 1.0 C A:CYS191 5.0 41.6 1.0 C A:CYS213 5.0 31.3 1.0

Zinc binding site 2 out of 2 in the Structure of RAD14 in Complex with Acetylaminophenyl-Guanine Containing Dna


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Structure of RAD14 in Complex with Acetylaminophenyl-Guanine Containing Dna within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn1303 b:36.1 occ:1.00 SG B:CYS191 2.2 40.1 1.0 SG B:CYS216 2.3 33.3 1.0 SG B:CYS213 2.3 34.2 1.0 SG B:CYS194 2.3 38.4 1.0 CB B:CYS191 3.2 39.2 1.0 CB B:CYS194 3.2 39.8 1.0 CB B:CYS216 3.2 33.1 1.0 CB B:CYS213 3.5 35.0 1.0 N B:CYS194 3.6 42.1 1.0 CA B:CYS194 4.0 42.0 1.0 N B:CYS213 4.0 35.5 1.0 N B:CYS216 4.3 31.7 1.0 CA B:CYS213 4.3 34.4 1.0 CA B:CYS216 4.3 33.2 1.0 CB B:ASN197 4.4 35.5 1.0 CB B:GLU193 4.5 45.5 1.0 ND2 B:ASN197 4.5 34.2 1.0 CA B:CYS191 4.6 40.7 1.0 C B:GLU193 4.6 44.8 1.0 O B:CYS213 4.8 30.2 1.0 CA B:GLU193 4.9 45.4 1.0 N B:GLU193 4.9 43.7 1.0 C B:CYS213 4.9 32.6 1.0 C B:CYS194 4.9 43.5 1.0 C B:CYS191 5.0 42.0 1.0 N B:ASN197 5.0 38.1 1.0 N B:HIS195 5.0 44.3 1.0

S.Schneider, N.Simon, C.Ebert. Structural Basis For Bulky Adduct Dna Lesion Recognition By the Nucleotide Excision Repair Protein RAD14. Chemistry V. 22 10782 2016.
ISSN: ISSN 0947-6539
PubMed: 27223336
DOI: 10.1002/CHEM.201602438