Zinc in PDB 5f9z: Crystal Structure of Prolyl-Trna Synthetase From Cryptosporidium Parvum Complexed with Halofuginone and Amppnp

The structure of Crystal Structure of Prolyl-Trna Synthetase From Cryptosporidium Parvum Complexed with Halofuginone and Amppnp, PDB code: 5f9z was solved by Seattle Structural Genomics Center For Infectious Disease (Ssgcid), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	46.61 / 2.40
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	89.400, 108.720, 126.350, 90.00, 90.00, 90.00
R / Rfree (%)	20.8 / 23.4

The structure of Crystal Structure of Prolyl-Trna Synthetase From Cryptosporidium Parvum Complexed with Halofuginone and Amppnp also contains other interesting chemical elements:

Chlorine	(Cl)	2 atoms
Bromine	(Br)	2 atoms
Magnesium	(Mg)	2 atoms

The binding sites of Zinc atom in the Crystal Structure of Prolyl-Trna Synthetase From Cryptosporidium Parvum Complexed with Halofuginone and Amppnp (pdb code 5f9z). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Prolyl-Trna Synthetase From Cryptosporidium Parvum Complexed with Halofuginone and Amppnp, PDB code: 5f9z:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of Prolyl-Trna Synthetase From Cryptosporidium Parvum Complexed with Halofuginone and Amppnp


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Prolyl-Trna Synthetase From Cryptosporidium Parvum Complexed with Halofuginone and Amppnp within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn703 b:45.7 occ:1.00 SG A:CYS621 2.3 41.9 1.0 SG A:CYS626 2.3 43.5 1.0 SG A:CYS674 2.5 47.1 1.0 SG A:CYS671 2.5 47.4 1.0 CB A:CYS626 3.2 44.6 1.0 CB A:CYS671 3.2 48.8 1.0 CB A:CYS621 3.3 42.7 1.0 CB A:CYS674 3.5 46.7 1.0 N A:CYS674 3.8 46.7 1.0 CD1 A:TRP620 3.9 39.0 1.0 N A:CYS621 3.9 40.7 1.0 NE1 A:TRP620 3.9 39.9 1.0 CA A:CYS674 4.2 48.2 1.0 CA A:CYS621 4.2 41.8 1.0 CA A:CYS626 4.6 45.7 1.0 CA A:CYS671 4.7 47.9 1.0 C A:CYS674 4.7 50.0 1.0 CB A:PHE673 4.8 41.2 1.0 CB A:LYS676 4.9 55.0 1.0 C A:CYS621 4.9 41.1 1.0 O A:CYS674 4.9 50.1 1.0 C A:PHE673 4.9 45.8 1.0 N A:GLU622 4.9 39.6 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of Prolyl-Trna Synthetase From Cryptosporidium Parvum Complexed with Halofuginone and Amppnp


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Prolyl-Trna Synthetase From Cryptosporidium Parvum Complexed with Halofuginone and Amppnp within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn704 b:52.3 occ:1.00 SG B:CYS621 2.4 43.8 1.0 SG B:CYS671 2.4 50.4 1.0 SG B:CYS626 2.4 48.0 1.0 SG B:CYS674 2.4 57.1 1.0 CB B:CYS626 3.0 48.2 1.0 CB B:CYS671 3.3 53.0 1.0 CB B:CYS674 3.5 58.0 1.0 CB B:CYS621 3.5 44.9 1.0 CD1 B:TRP620 3.9 40.5 1.0 N B:CYS674 3.9 57.3 1.0 NE1 B:TRP620 4.0 41.1 1.0 N B:CYS621 4.0 42.2 1.0 CA B:CYS674 4.2 59.1 1.0 CA B:CYS621 4.4 43.6 1.0 CA B:CYS626 4.4 49.4 1.0 CA B:CYS671 4.7 54.3 1.0 CB B:PHE673 4.8 53.2 1.0 C B:PHE673 4.8 56.8 1.0 C B:CYS674 4.9 60.8 1.0

Seattle Structural Genomics Center For Infectious Disease(Ssgcid), D.M.Dranow, D.Fox Iii, D.Lorimer, T.E.Edwards. Crystal Structure of Prolyl-Trna Synthetase From Cryptosporidium Parvum Complexed with Halofuginone and Amppnp To Be Published.