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Atomistry » Zinc » PDB 5ehf-5evd » 5ety | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Zinc » PDB 5ehf-5evd » 5ety » |
Zinc in PDB 5ety: Crystal Structure of Human Tankyrase-1 Bound to K-756Enzymatic activity of Crystal Structure of Human Tankyrase-1 Bound to K-756
All present enzymatic activity of Crystal Structure of Human Tankyrase-1 Bound to K-756:
2.4.2.30; Protein crystallography data
The structure of Crystal Structure of Human Tankyrase-1 Bound to K-756, PDB code: 5ety
was solved by
Y.Takahashi,
H.Miyagi,
M.Suzuki,
J.Saito,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Zinc Binding Sites:
The binding sites of Zinc atom in the Crystal Structure of Human Tankyrase-1 Bound to K-756
(pdb code 5ety). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 4 binding sites of Zinc where determined in the Crystal Structure of Human Tankyrase-1 Bound to K-756, PDB code: 5ety: Jump to Zinc binding site number: 1; 2; 3; 4; Zinc binding site 1 out of 4 in 5etyGo back to Zinc Binding Sites List in 5ety
Zinc binding site 1 out
of 4 in the Crystal Structure of Human Tankyrase-1 Bound to K-756
Mono view Stereo pair view
Zinc binding site 2 out of 4 in 5etyGo back to Zinc Binding Sites List in 5ety
Zinc binding site 2 out
of 4 in the Crystal Structure of Human Tankyrase-1 Bound to K-756
Mono view Stereo pair view
Zinc binding site 3 out of 4 in 5etyGo back to Zinc Binding Sites List in 5ety
Zinc binding site 3 out
of 4 in the Crystal Structure of Human Tankyrase-1 Bound to K-756
Mono view Stereo pair view
Zinc binding site 4 out of 4 in 5etyGo back to Zinc Binding Sites List in 5ety
Zinc binding site 4 out
of 4 in the Crystal Structure of Human Tankyrase-1 Bound to K-756
Mono view Stereo pair view
Reference:
R.Okada-Iwasaki,
Y.Takahashi,
Y.Watanabe,
H.Ishida,
J.Saito,
R.Nakai,
A.Asai.
The Discovery and Characterization of K-756, A Novel Wnt/ Beta-Catenin Pathway Inhibitor Targeting Tankyrase Mol.Cancer Ther. V. 15 1525 2016.
Page generated: Sun Oct 27 15:30:50 2024
ISSN: ESSN 1538-8514 PubMed: 27196752 DOI: 10.1158/1535-7163.MCT-15-0938 |
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