Zinc in PDB 5e7w: X-Ray Structure of Human Recombinant 2ZN Insulin at 0.92 Angstrom

The structure of X-Ray Structure of Human Recombinant 2ZN Insulin at 0.92 Angstrom, PDB code: 5e7w was solved by D.R.Lisgarten, C.E.Naylor, R.A.Palmer, C.M.C.Lobley, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	10.00 / 0.95
Space group	H 3
Cell size a, b, c (Å), α, β, γ (°)	81.820, 81.820, 33.850, 90.00, 90.00, 120.00
R / Rfree (%)	n/a / n/a

The binding sites of Zinc atom in the X-Ray Structure of Human Recombinant 2ZN Insulin at 0.92 Angstrom (pdb code 5e7w). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the X-Ray Structure of Human Recombinant 2ZN Insulin at 0.92 Angstrom, PDB code: 5e7w:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the X-Ray Structure of Human Recombinant 2ZN Insulin at 0.92 Angstrom


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of X-Ray Structure of Human Recombinant 2ZN Insulin at 0.92 Angstrom within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn100 b:8.7 occ:0.33 NE2 B:HIS10 2.1 7.6 1.0 O B:ACT101 2.1 10.8 0.3 C B:ACT101 2.8 18.8 0.3 OXT B:ACT101 3.0 32.3 0.3 CE1 B:HIS10 3.0 9.3 1.0 CD2 B:HIS10 3.1 7.3 1.0 HE1 B:HIS10 3.2 11.5 1.0 HD2 B:HIS10 3.3 9.0 1.0 O B:HOH202 4.1 57.3 1.0 CH3 B:ACT101 4.2 12.1 0.3 ND1 B:HIS10 4.2 8.7 1.0 CG B:HIS10 4.3 7.4 1.0 O B:HOH220 4.4 12.2 0.5 HD1 B:HIS10 5.0 10.7 1.0 O B:HOH255 5.0 28.4 0.3

Zinc binding site 2 out of 2 in the X-Ray Structure of Human Recombinant 2ZN Insulin at 0.92 Angstrom


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of X-Ray Structure of Human Recombinant 2ZN Insulin at 0.92 Angstrom within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn202 b:8.7 occ:0.33 NE2 D:HIS10 2.1 7.9 1.0 O D:HOH335 2.2 18.6 1.0 CE1 D:HIS10 3.1 8.4 1.0 CD2 D:HIS10 3.1 8.3 1.0 HE1 D:HIS10 3.2 10.4 1.0 HD2 D:HIS10 3.3 10.2 1.0 O D:HOH364 4.1 36.7 1.0 ND1 D:HIS10 4.2 8.9 1.0 CG D:HIS10 4.2 7.6 1.0 O D:HOH325 4.7 28.2 1.0 O D:HOH338 4.7 37.5 1.0 O D:HOH351 4.9 16.4 0.3 HD1 D:HIS10 5.0 10.9 1.0

D.R.Lisgarten, R.A.Palmer, C.M.C.Lobley, C.E.Naylor, B.Z.Chowdhry, Z.I.Al-Kurdi, A.A.Badwan, B.J.Howlin, N.C.J.Gibbons, J.W.Saldanha, J.N.Lisgarten, A.K.Basak. Ultra-High Resolution X-Ray Structures of Two Forms of Human Recombinant Insulin at 100 K. Chem Cent J V. 11 73 2017.
ISSN: ISSN 1752-153X
PubMed: 29086855
DOI: 10.1186/S13065-017-0296-Y