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Atomistry » Zinc » PDB 5drp-5e84 » 5e2r » |
Zinc in PDB 5e2r: The Crystal Structure of the Human Carbonic Anhydrase II in Complex with A 1,1'-Biphenyl-4-Sulfonamide InhibitorEnzymatic activity of The Crystal Structure of the Human Carbonic Anhydrase II in Complex with A 1,1'-Biphenyl-4-Sulfonamide Inhibitor
All present enzymatic activity of The Crystal Structure of the Human Carbonic Anhydrase II in Complex with A 1,1'-Biphenyl-4-Sulfonamide Inhibitor:
4.2.1.1; Protein crystallography data
The structure of The Crystal Structure of the Human Carbonic Anhydrase II in Complex with A 1,1'-Biphenyl-4-Sulfonamide Inhibitor, PDB code: 5e2r
was solved by
V.Alterio,
G.De Simone,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Zinc Binding Sites:
The binding sites of Zinc atom in the The Crystal Structure of the Human Carbonic Anhydrase II in Complex with A 1,1'-Biphenyl-4-Sulfonamide Inhibitor
(pdb code 5e2r). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the The Crystal Structure of the Human Carbonic Anhydrase II in Complex with A 1,1'-Biphenyl-4-Sulfonamide Inhibitor, PDB code: 5e2r: Zinc binding site 1 out of 1 in 5e2rGo back to Zinc Binding Sites List in 5e2r
Zinc binding site 1 out
of 1 in the The Crystal Structure of the Human Carbonic Anhydrase II in Complex with A 1,1'-Biphenyl-4-Sulfonamide Inhibitor
Mono view Stereo pair view
Reference:
G.La Regina,
A.Coluccia,
V.Famiglini,
S.Pelliccia,
L.Monti,
D.Vullo,
E.Nuti,
V.Alterio,
G.De Simone,
S.M.Monti,
P.Pan,
S.Parkkila,
C.T.Supuran,
A.Rossello,
R.Silvestri.
Discovery of 1,1'-Biphenyl-4-Sulfonamides As A New Class of Potent and Selective Carbonic Anhydrase Xiv Inhibitors. J.Med.Chem. V. 58 8564 2015.
Page generated: Wed Dec 16 06:09:00 2020
ISSN: ISSN 0022-2623 PubMed: 26497049 DOI: 10.1021/ACS.JMEDCHEM.5B01144 |
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