Zinc in PDB 5dsl: Structure of CO2 Released Holo-Form of Human Carbonic Anhydrase II with 10 Min Warming

All present enzymatic activity of Structure of CO2 Released Holo-Form of Human Carbonic Anhydrase II with 10 Min Warming:
4.2.1.1;

The structure of Structure of CO2 Released Holo-Form of Human Carbonic Anhydrase II with 10 Min Warming, PDB code: 5dsl was solved by C.U.Kim, S.Y.Park, R.Mckenna, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	23.28 / 1.45
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	42.228, 41.245, 72.048, 90.00, 104.22, 90.00
R / Rfree (%)	10.2 / 14.7

The binding sites of Zinc atom in the Structure of CO2 Released Holo-Form of Human Carbonic Anhydrase II with 10 Min Warming (pdb code 5dsl). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Structure of CO2 Released Holo-Form of Human Carbonic Anhydrase II with 10 Min Warming, PDB code: 5dsl:

Zinc binding site 1 out of 1 in the Structure of CO2 Released Holo-Form of Human Carbonic Anhydrase II with 10 Min Warming


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of CO2 Released Holo-Form of Human Carbonic Anhydrase II with 10 Min Warming within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn301 b:7.0 occ:1.00 O A:HOH438 2.0 13.6 1.0 NE2 A:HIS94 2.1 6.6 1.0 ND1 A:HIS119 2.1 6.1 1.0 NE2 A:HIS96 2.1 6.9 1.0 O A:HOH669 2.6 21.8 1.0 CE1 A:HIS119 3.0 6.0 1.0 CD2 A:HIS94 3.0 6.5 1.0 CD2 A:HIS96 3.0 7.0 1.0 CE1 A:HIS96 3.1 7.5 1.0 CE1 A:HIS94 3.1 6.7 1.0 CG A:HIS119 3.1 5.4 1.0 CB A:HIS119 3.6 5.3 1.0 O A:HOH574 3.7 20.6 1.0 O A:HOH637 3.8 17.7 1.0 OG1 A:THR199 3.8 7.6 1.0 OE1 A:GLU106 4.1 7.6 1.0 NE2 A:HIS119 4.1 6.4 1.0 CG A:HIS94 4.1 6.5 1.0 ND1 A:HIS94 4.1 7.0 1.0 ND1 A:HIS96 4.2 7.4 1.0 CD2 A:HIS119 4.2 6.5 1.0 CG A:HIS96 4.2 6.2 1.0 O A:HOH698 4.4 14.0 0.5 CD A:GLU106 5.0 6.7 1.0

C.U.Kim, H.Song, B.S.Avvaru, S.M.Gruner, S.Park, R.Mckenna. Tracking Solvent and Protein Movement During CO2 Release in Carbonic Anhydrase II Crystals Proc. Natl. Acad. Sci. V. 113 5257 2016U.S.A..
ISSN: ESSN 1091-6490
PubMed: 27114542
DOI: 10.1073/PNAS.1520786113