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Atomistry » Zinc » PDB 5cvi-5d7w » 5czm | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Zinc » PDB 5cvi-5d7w » 5czm » |
Zinc in PDB 5czm: Crystal Structure of A Mutated Catalytic Domain of Human MMP12 in Complex with RXP470Enzymatic activity of Crystal Structure of A Mutated Catalytic Domain of Human MMP12 in Complex with RXP470
All present enzymatic activity of Crystal Structure of A Mutated Catalytic Domain of Human MMP12 in Complex with RXP470:
3.4.24.65; Protein crystallography data
The structure of Crystal Structure of A Mutated Catalytic Domain of Human MMP12 in Complex with RXP470, PDB code: 5czm
was solved by
C.Rouanet-Mehouas,
L.Roselia,
L.Devel,
V.Dive,
E.A.Stura,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5czm:
The structure of Crystal Structure of A Mutated Catalytic Domain of Human MMP12 in Complex with RXP470 also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Crystal Structure of A Mutated Catalytic Domain of Human MMP12 in Complex with RXP470
(pdb code 5czm). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of A Mutated Catalytic Domain of Human MMP12 in Complex with RXP470, PDB code: 5czm: Jump to Zinc binding site number: 1; 2; Zinc binding site 1 out of 2 in 5czmGo back to Zinc Binding Sites List in 5czm
Zinc binding site 1 out
of 2 in the Crystal Structure of A Mutated Catalytic Domain of Human MMP12 in Complex with RXP470
Mono view Stereo pair view
Zinc binding site 2 out of 2 in 5czmGo back to Zinc Binding Sites List in 5czm
Zinc binding site 2 out
of 2 in the Crystal Structure of A Mutated Catalytic Domain of Human MMP12 in Complex with RXP470
Mono view Stereo pair view
Reference:
C.Rouanet-Mehouas,
B.Czarny,
F.Beau,
E.Cassar-Lajeunesse,
E.A.Stura,
V.Dive,
L.Devel.
Zinc-Metalloproteinase Inhibitors: Evaluation of the Complex Role Played By the Zinc-Binding Group on Potency and Selectivity. J. Med. Chem. V. 60 403 2017.
Page generated: Sun Oct 27 14:30:42 2024
ISSN: ISSN 1520-4804 PubMed: 27996256 DOI: 10.1021/ACS.JMEDCHEM.6B01420 |
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