Zinc in PDB 5cmr: Crystal Structure of Linker-Mediated Zn-Bound Human H-Ferritin Variant 122H-Delta C-Star

All present enzymatic activity of Crystal Structure of Linker-Mediated Zn-Bound Human H-Ferritin Variant 122H-Delta C-Star:
1.16.3.1;

The structure of Crystal Structure of Linker-Mediated Zn-Bound Human H-Ferritin Variant 122H-Delta C-Star, PDB code: 5cmr was solved by P.A.Sontz, J.B.Bailey, S.Ahn, F.A.Tezcan, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	54.91 / 3.79
Space group	I 4 3 2
Cell size a, b, c (Å), α, β, γ (°)	155.320, 155.320, 155.320, 90.00, 90.00, 90.00
R / Rfree (%)	20.7 / 25.6

The structure of Crystal Structure of Linker-Mediated Zn-Bound Human H-Ferritin Variant 122H-Delta C-Star also contains other interesting chemical elements:

Sodium

(Na)

3 atoms

The binding sites of Zinc atom in the Crystal Structure of Linker-Mediated Zn-Bound Human H-Ferritin Variant 122H-Delta C-Star (pdb code 5cmr). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Linker-Mediated Zn-Bound Human H-Ferritin Variant 122H-Delta C-Star, PDB code: 5cmr:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of Linker-Mediated Zn-Bound Human H-Ferritin Variant 122H-Delta C-Star


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Linker-Mediated Zn-Bound Human H-Ferritin Variant 122H-Delta C-Star within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn201 b:61.2 occ:1.00 OE1 A:GLU27 2.0 83.8 1.0 ND1 A:HIS65 2.2 73.7 1.0 OE1 A:GLU62 2.3 48.7 1.0 CD A:GLU27 2.8 70.4 1.0 OE2 A:GLU27 2.8 63.9 1.0 NA A:NA205 2.9 47.0 1.0 CE1 A:HIS65 3.1 91.3 1.0 OE1 A:GLN141 3.1 73.3 1.0 CG A:HIS65 3.3 74.1 1.0 CD A:GLU62 3.3 66.6 1.0 CB A:HIS65 3.7 68.2 1.0 OE2 A:GLU62 3.7 65.8 1.0 CG1 A:VAL110 4.0 0.3 1.0 CG A:GLU27 4.2 60.4 1.0 NE2 A:HIS65 4.3 0.8 1.0 CD A:GLN141 4.3 82.3 1.0 CD2 A:HIS65 4.4 0.8 1.0 CG A:GLU62 4.7 92.2 1.0 CA A:GLU62 4.7 73.2 1.0 CB A:GLU27 4.7 64.7 1.0 OE1 A:GLU107 4.8 0.2 1.0 CB A:GLU62 4.9 74.6 1.0 NE2 A:GLN141 5.0 72.6 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of Linker-Mediated Zn-Bound Human H-Ferritin Variant 122H-Delta C-Star


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Linker-Mediated Zn-Bound Human H-Ferritin Variant 122H-Delta C-Star within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn202 b:93.5 occ:0.33 NE2 A:HIS122 2.0 72.1 1.0 OAM A:BYD206 2.1 76.4 0.2 OAN A:BYD206 2.3 85.5 0.2 CE1 A:HIS122 2.4 93.0 1.0 CAK A:BYD206 2.9 72.9 0.2 NAL A:BYD206 3.0 78.1 0.2 HAN A:BYD206 3.1 0.6 0.2 CD2 A:HIS122 3.4 74.2 1.0 ND1 A:HIS122 3.7 0.4 1.0 HAL A:BYD206 4.0 93.7 0.2 CG A:HIS122 4.1 86.0 1.0 CAC A:BYD206 4.2 66.5 0.2 HAD A:BYD206 4.9 94.3 0.2 HAB A:BYD206 4.9 93.2 0.2

P.A.Sontz, J.B.Bailey, S.Ahn, F.A.Tezcan. A Metal Organic Framework with Spherical Protein Nodes: Rational Chemical Design of 3D Protein Crystals. J.Am.Chem.Soc. V. 137 11598 2015.
ISSN: ESSN 1520-5126
PubMed: 26305584
DOI: 10.1021/JACS.5B07463