Zinc in PDB 5aeb: Crystal Structure of the Class B3 Di-Zinc Metallo-Beta-Lactamase Lra- 12 From An Alaskan Soil Metagenome.

Enzymatic activity of Crystal Structure of the Class B3 Di-Zinc Metallo-Beta-Lactamase Lra- 12 From An Alaskan Soil Metagenome.

All present enzymatic activity of Crystal Structure of the Class B3 Di-Zinc Metallo-Beta-Lactamase Lra- 12 From An Alaskan Soil Metagenome.:
3.5.2.6;

Protein crystallography data

The structure of Crystal Structure of the Class B3 Di-Zinc Metallo-Beta-Lactamase Lra- 12 From An Alaskan Soil Metagenome., PDB code: 5aeb was solved by P.Power, R.Herman, F.Kerff, F.Bouillenne, M.M.Rodriguez, M.Galleni, J.Handelsman, G.Gutkind, P.Charlier, E.Sauvage, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 42.93 / 2.10
Space group P 1 21 1
Cell size a, b, c (Å), α, β, γ (°) 47.148, 80.616, 78.288, 90.00, 98.83, 90.00
R / Rfree (%) 18.4 / 23.5

Other elements in 5aeb:

The structure of Crystal Structure of the Class B3 Di-Zinc Metallo-Beta-Lactamase Lra- 12 From An Alaskan Soil Metagenome. also contains other interesting chemical elements:

Cobalt (Co) 1 atom

Zinc Binding Sites:

The binding sites of Zinc atom in the Crystal Structure of the Class B3 Di-Zinc Metallo-Beta-Lactamase Lra- 12 From An Alaskan Soil Metagenome. (pdb code 5aeb). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 4 binding sites of Zinc where determined in the Crystal Structure of the Class B3 Di-Zinc Metallo-Beta-Lactamase Lra- 12 From An Alaskan Soil Metagenome., PDB code: 5aeb:
Jump to Zinc binding site number: 1; 2; 3; 4;

Zinc binding site 1 out of 4 in 5aeb

Go back to Zinc Binding Sites List in 5aeb
Zinc binding site 1 out of 4 in the Crystal Structure of the Class B3 Di-Zinc Metallo-Beta-Lactamase Lra- 12 From An Alaskan Soil Metagenome.


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of the Class B3 Di-Zinc Metallo-Beta-Lactamase Lra- 12 From An Alaskan Soil Metagenome. within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn1307

b:2.0
occ:0.70
 O A:HOH2041 1.9 4.1 1.0
O A:HOH2040 1.9 2.0 1.0
NE2 A:HIS121 1.9 19.6 1.0
OD2 A:ASP120 2.0 20.5 1.0
NE2 A:HIS263 2.0 20.1 1.0
CE1 A:HIS121 2.8 19.5 1.0
CD2 A:HIS263 3.0 19.8 1.0
CG A:ASP120 3.0 20.9 1.0
CD2 A:HIS121 3.0 19.5 1.0
CE1 A:HIS263 3.1 20.5 1.0
OD1 A:ASP120 3.4 20.9 1.0
O A:HOH2098 3.4 14.6 1.0
ZN A:ZN1308 3.6 4.3 0.7
OE1 A:GLN116 3.6 19.5 1.0
NE2 A:GLN116 3.9 19.2 1.0
O A:HOH2086 4.0 10.8 1.0
ND1 A:HIS121 4.0 19.3 1.0
CG A:HIS121 4.1 19.3 1.0
CG A:HIS263 4.2 20.1 1.0
CD A:GLN116 4.2 19.2 1.0
O A:HOH2045 4.2 17.4 1.0
ND1 A:HIS263 4.2 20.5 1.0
CB A:ASP120 4.3 20.9 1.0
NE2 A:HIS196 4.7 20.8 1.0

Zinc binding site 2 out of 4 in 5aeb

Go back to Zinc Binding Sites List in 5aeb
Zinc binding site 2 out of 4 in the Crystal Structure of the Class B3 Di-Zinc Metallo-Beta-Lactamase Lra- 12 From An Alaskan Soil Metagenome.


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of the Class B3 Di-Zinc Metallo-Beta-Lactamase Lra- 12 From An Alaskan Soil Metagenome. within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn1308

b:4.3
occ:0.70
 NE2 A:HIS196 1.8 20.8 1.0
OE1 A:GLN116 1.8 19.5 1.0
O A:HOH2040 1.9 2.0 1.0
ND1 A:HIS118 1.9 20.9 1.0
O A:HOH2045 2.7 17.4 1.0
CD2 A:HIS196 2.8 20.3 1.0
CE1 A:HIS118 2.8 21.2 1.0
CE1 A:HIS196 2.8 20.9 1.0
CD A:GLN116 2.9 19.2 1.0
CG A:HIS118 3.0 21.0 1.0
O A:HOH2041 3.2 4.1 1.0
CB A:HIS118 3.5 20.5 1.0
NE2 A:GLN116 3.6 19.2 1.0
ZN A:ZN1307 3.6 2.0 0.7
ND1 A:HIS196 3.9 20.5 1.0
CG A:GLN116 3.9 18.9 1.0
CG A:HIS196 3.9 20.1 1.0
NE2 A:HIS118 4.0 21.4 1.0
OD1 A:ASP120 4.1 20.9 1.0
CD2 A:HIS118 4.1 21.1 1.0
CD2 A:HIS121 4.2 19.5 1.0
NE2 A:HIS121 4.3 19.6 1.0
O A:HOH2098 4.3 14.6 1.0
O A:HOH2086 4.3 10.8 1.0
OD2 A:ASP120 4.6 20.5 1.0
CG2 A:VAL225 4.7 29.9 1.0
CG A:ASP120 4.8 20.9 1.0
CB A:GLN116 4.9 18.7 1.0
CA A:HIS118 4.9 20.3 1.0

Zinc binding site 3 out of 4 in 5aeb

Go back to Zinc Binding Sites List in 5aeb
Zinc binding site 3 out of 4 in the Crystal Structure of the Class B3 Di-Zinc Metallo-Beta-Lactamase Lra- 12 From An Alaskan Soil Metagenome.


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Crystal Structure of the Class B3 Di-Zinc Metallo-Beta-Lactamase Lra- 12 From An Alaskan Soil Metagenome. within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Zn1307

b:2.0
occ:0.70
 OE1 B:GLN116 1.8 18.3 1.0
ND1 B:HIS118 1.8 18.9 1.0
NE2 B:HIS196 1.9 18.4 1.0
O B:HOH2050 2.0 3.4 1.0
O B:HOH2054 2.2 10.6 1.0
CE1 B:HIS118 2.7 19.2 1.0
CD B:GLN116 2.8 18.1 1.0
CD2 B:HIS196 2.9 18.0 1.0
CE1 B:HIS196 3.0 18.4 1.0
CG B:HIS118 3.0 18.8 1.0
O B:HOH2049 3.0 7.8 1.0
CB B:HIS118 3.5 18.6 1.0
NE2 B:GLN116 3.5 18.1 1.0
ZN B:ZN1308 3.7 2.0 0.7
O B:HOH2057 3.8 29.2 1.0
NE2 B:HIS118 3.9 19.3 1.0
CG B:GLN116 3.9 18.0 1.0
CD2 B:HIS118 4.0 19.1 1.0
CG B:HIS196 4.1 17.8 1.0
ND1 B:HIS196 4.1 18.1 1.0
OD1 B:ASP120 4.1 18.7 1.0
NE2 B:HIS121 4.1 18.2 1.0
CD2 B:HIS121 4.1 18.0 1.0
OD2 B:ASP120 4.4 18.8 1.0
O B:HOH2094 4.4 12.2 1.0
CG B:ASP120 4.7 18.8 1.0
CG1 B:VAL225 4.8 32.9 1.0
CA B:HIS118 4.9 18.5 1.0

Zinc binding site 4 out of 4 in 5aeb

Go back to Zinc Binding Sites List in 5aeb
Zinc binding site 4 out of 4 in the Crystal Structure of the Class B3 Di-Zinc Metallo-Beta-Lactamase Lra- 12 From An Alaskan Soil Metagenome.


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Crystal Structure of the Class B3 Di-Zinc Metallo-Beta-Lactamase Lra- 12 From An Alaskan Soil Metagenome. within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Zn1308

b:2.0
occ:0.70
 O B:HOH2049 1.8 7.8 1.0
OD2 B:ASP120 1.9 18.8 1.0
NE2 B:HIS121 1.9 18.2 1.0
O B:HOH2050 1.9 3.4 1.0
NE2 B:HIS263 2.0 18.9 1.0
O B:HOH2057 2.3 29.2 1.0
CE1 B:HIS121 2.7 18.1 1.0
CE1 B:HIS263 2.9 19.5 1.0
CG B:ASP120 2.9 18.8 1.0
CD2 B:HIS121 3.0 18.0 1.0
CD2 B:HIS263 3.0 18.5 1.0
OD1 B:ASP120 3.5 18.7 1.0
ZN B:ZN1307 3.7 2.0 0.7
OE1 B:GLN116 3.7 18.3 1.0
ND1 B:HIS121 3.8 17.9 1.0
O B:HOH2054 4.0 10.6 1.0
CG B:HIS121 4.0 17.8 1.0
O B:HOH2094 4.0 12.2 1.0
NE2 B:GLN116 4.1 18.1 1.0
ND1 B:HIS263 4.1 19.5 1.0
CG B:HIS263 4.2 18.9 1.0
CB B:ASP120 4.2 18.8 1.0
CD B:GLN116 4.3 18.1 1.0
NE2 B:HIS196 4.8 18.4 1.0

Reference:

M.M.Rodriguez, R.Herman, B.Ghiglione, F.Kerff, G.D'amico Gonzalez, F.Bouillenne, M.Galleni, J.Handelsman, P.Charlier, G.Gutkind, E.Sauvage, P.Power. Crystal Structure and Kinetic Analysis of the Class B3 Di-Zinc Metallo-Beta-Lactamase Lra-12 From An Alaskan Soil Metagenome. Plos One V. 12 82043 2017.
ISSN: ESSN 1932-6203
PubMed: 28750094
DOI: 10.1371/JOURNAL.PONE.0182043
Page generated: Wed Dec 16 06:02:57 2020

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy