Zinc in PDB 5a3d: Structural Insights Into the Recognition of Cisplatin and Aaf-Dg Lesions By RAD14 (Xpa)

The structure of Structural Insights Into the Recognition of Cisplatin and Aaf-Dg Lesions By RAD14 (Xpa), PDB code: 5a3d was solved by J.Kuper, S.C.Koch, K.L.Gasteiger, N.Wichlein, S.Schneider, C.Kisker, T.Carell, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	53.73 / 1.80
Space group	P 41
Cell size a, b, c (Å), α, β, γ (°)	53.727, 53.727, 130.551, 90.00, 90.00, 90.00
R / Rfree (%)	21 / 24.1

The structure of Structural Insights Into the Recognition of Cisplatin and Aaf-Dg Lesions By RAD14 (Xpa) also contains other interesting chemical elements:

Iodine

(I)

6 atoms

The binding sites of Zinc atom in the Structural Insights Into the Recognition of Cisplatin and Aaf-Dg Lesions By RAD14 (Xpa) (pdb code 5a3d). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Structural Insights Into the Recognition of Cisplatin and Aaf-Dg Lesions By RAD14 (Xpa), PDB code: 5a3d:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Structural Insights Into the Recognition of Cisplatin and Aaf-Dg Lesions By RAD14 (Xpa)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structural Insights Into the Recognition of Cisplatin and Aaf-Dg Lesions By RAD14 (Xpa) within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn500 b:32.2 occ:1.00 SG A:CYS216 2.2 33.0 1.0 SG A:CYS213 2.3 30.6 1.0 SG A:CYS191 2.4 31.3 1.0 SG A:CYS194 2.4 31.2 1.0 CB A:CYS216 3.1 31.2 1.0 CB A:CYS194 3.1 33.2 1.0 CB A:CYS191 3.2 33.9 1.0 N A:CYS194 3.5 34.9 1.0 CB A:CYS213 3.6 29.8 1.0 CA A:CYS194 3.9 36.0 1.0 N A:CYS213 4.0 30.2 1.0 CA A:CYS216 4.3 31.8 1.0 N A:CYS216 4.3 29.4 1.0 CA A:CYS213 4.3 29.3 1.0 CB A:GLU193 4.5 38.8 1.0 CB A:ASN197 4.5 30.9 1.0 ND2 A:ASN197 4.5 31.4 1.0 C A:GLU193 4.6 39.1 1.0 CA A:CYS191 4.6 34.7 1.0 O A:CYS213 4.8 28.0 1.0 CA A:GLU193 4.8 38.8 1.0 C A:CYS213 4.9 28.1 1.0 N A:GLU193 4.9 37.6 1.0 C A:CYS194 5.0 36.0 1.0 C A:CYS191 5.0 35.6 1.0

Zinc binding site 2 out of 2 in the Structural Insights Into the Recognition of Cisplatin and Aaf-Dg Lesions By RAD14 (Xpa)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Structural Insights Into the Recognition of Cisplatin and Aaf-Dg Lesions By RAD14 (Xpa) within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn500 b:32.1 occ:1.00 SG B:CYS216 2.3 33.0 1.0 SG B:CYS213 2.3 29.0 1.0 SG B:CYS194 2.4 32.3 1.0 SG B:CYS191 2.4 30.7 1.0 CB B:CYS194 3.1 33.8 1.0 CB B:CYS216 3.2 31.7 1.0 CB B:CYS191 3.2 30.2 1.0 CB B:CYS213 3.5 28.6 1.0 N B:CYS194 3.6 35.5 1.0 CA B:CYS194 4.0 36.3 1.0 N B:CYS213 4.0 30.4 1.0 CA B:CYS213 4.3 29.0 1.0 CA B:CYS216 4.3 32.5 1.0 N B:CYS216 4.3 30.8 1.0 CB B:ASN197 4.5 30.0 1.0 CB B:GLU193 4.5 38.9 1.0 ND2 B:ASN197 4.5 30.0 1.0 CA B:CYS191 4.7 32.4 1.0 C B:GLU193 4.7 40.1 1.0 O B:CYS213 4.8 27.9 1.0 N B:GLU193 4.9 37.6 1.0 C B:CYS213 4.9 27.8 1.0 CA B:GLU193 4.9 39.3 1.0 C B:CYS194 4.9 35.9 1.0 N B:HIS195 5.0 36.9 1.0

S.C.Koch, J.Kuper, K.L.Gasteiger, N.Simon, R.Strasser, D.Eisen, S.Geiger, S.Schneider, C.Kisker, T.Carell. Structural Insights Into the Recognition of Cisplatin and Aaf-Dg Lesion By RAD14 (Xpa). Proc.Natl.Acad.Sci.Usa V. 112 8272 2015.
ISSN: ISSN 0027-8424
PubMed: 26100901
DOI: 10.1073/PNAS.1508509112