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Zinc in PDB 4zh3: Crystal Structure of Escherichia Coli Rna Polymerase in Complex with CBRH16-Br
Enzymatic activity of Crystal Structure of Escherichia Coli Rna Polymerase in Complex with CBRH16-Br
All present enzymatic activity of Crystal Structure of Escherichia Coli Rna Polymerase in Complex with CBRH16-Br:
2.7.7.6;
2.7.7.6;
Protein crystallography data
The structure of Crystal Structure of Escherichia Coli Rna Polymerase in Complex with CBRH16-Br, PDB code: 4zh3
was solved by
Y.Feng,
R.H.Ebright,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 49.75 / 4.08 |
| Space group | P 21 21 21 |
| Cell size a, b, c (Å), α, β, γ (°) | 186.339, 205.790, 307.630, 90.00, 90.00, 90.00 |
| R / Rfree (%) | 23.8 / 26.7 |
Other elements in 4zh3:
The structure of Crystal Structure of Escherichia Coli Rna Polymerase in Complex with CBRH16-Br also contains other interesting chemical elements:
| Fluorine | (F) | 8 atoms |
| Magnesium | (Mg) | 2 atoms |
| Bromine | (Br) | 2 atoms |
Zinc Binding Sites:
The binding sites of Zinc atom in the Crystal Structure of Escherichia Coli Rna Polymerase in Complex with CBRH16-Br
(pdb code 4zh3). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 4 binding sites of Zinc where determined in the Crystal Structure of Escherichia Coli Rna Polymerase in Complex with CBRH16-Br, PDB code: 4zh3:
Jump to Zinc binding site number: 1; 2; 3; 4;
In total 4 binding sites of Zinc where determined in the Crystal Structure of Escherichia Coli Rna Polymerase in Complex with CBRH16-Br, PDB code: 4zh3:
Jump to Zinc binding site number: 1; 2; 3; 4;
Zinc binding site 1 out of 4 in 4zh3
Go back to
Zinc Binding Sites List in 4zh3
Zinc binding site 1 out
of 4 in the Crystal Structure of Escherichia Coli Rna Polymerase in Complex with CBRH16-Br
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Zinc with other atoms in the Zn binding
site number 1 of Crystal Structure of Escherichia Coli Rna Polymerase in Complex with CBRH16-Br within 5.0Å range:
|
Zinc binding site 2 out of 4 in 4zh3
Go back to
Zinc Binding Sites List in 4zh3
Zinc binding site 2 out
of 4 in the Crystal Structure of Escherichia Coli Rna Polymerase in Complex with CBRH16-Br
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Zinc with other atoms in the Zn binding
site number 2 of Crystal Structure of Escherichia Coli Rna Polymerase in Complex with CBRH16-Br within 5.0Å range:
|
Zinc binding site 3 out of 4 in 4zh3
Go back to
Zinc Binding Sites List in 4zh3
Zinc binding site 3 out
of 4 in the Crystal Structure of Escherichia Coli Rna Polymerase in Complex with CBRH16-Br
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Zinc with other atoms in the Zn binding
site number 3 of Crystal Structure of Escherichia Coli Rna Polymerase in Complex with CBRH16-Br within 5.0Å range:
|
Zinc binding site 4 out of 4 in 4zh3
Go back to
Zinc Binding Sites List in 4zh3
Zinc binding site 4 out
of 4 in the Crystal Structure of Escherichia Coli Rna Polymerase in Complex with CBRH16-Br
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Zinc with other atoms in the Zn binding
site number 4 of Crystal Structure of Escherichia Coli Rna Polymerase in Complex with CBRH16-Br within 5.0Å range:
|
Reference:
Y.Feng,
D.Degen,
X.Wang,
M.Gigliotti,
S.Liu,
Y.Zhang,
D.Das,
T.Michalchuk,
Y.W.Ebright,
M.Talaue,
N.Connell,
R.H.Ebright.
Structural Basis of Transcription Inhibition By Cbr Hydroxamidines and Cbr Pyrazoles. Structure V. 23 1470 2015.
ISSN: ISSN 0969-2126
PubMed: 26190576
DOI: 10.1016/J.STR.2015.06.009
Page generated: Sun Oct 27 11:47:57 2024
ISSN: ISSN 0969-2126
PubMed: 26190576
DOI: 10.1016/J.STR.2015.06.009
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