Zinc in PDB 4yh8: Structure of Yeast U2AF Complex

The structure of Structure of Yeast U2AF Complex, PDB code: 4yh8 was solved by H.Yoshida, S.Y.Park, T.Urano, E.Obayashi, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	35.55 / 1.70
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	91.616, 112.704, 57.198, 90.00, 90.00, 90.00
R / Rfree (%)	19.1 / 21.6

The binding sites of Zinc atom in the Structure of Yeast U2AF Complex (pdb code 4yh8). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Structure of Yeast U2AF Complex, PDB code: 4yh8:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Structure of Yeast U2AF Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of Yeast U2AF Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn301 b:31.5 occ:1.00 NE2 A:HIS37 2.0 33.6 1.0 SG A:CYS18 2.3 28.2 1.0 SG A:CYS33 2.4 35.2 1.0 SG A:CYS27 2.5 33.8 1.0 CE1 A:HIS37 2.8 35.5 1.0 CB A:CYS33 3.1 41.8 1.0 CD2 A:HIS37 3.1 35.6 1.0 CB A:CYS27 3.2 34.4 1.0 CB A:CYS18 3.3 31.2 1.0 ND1 A:HIS37 4.0 35.6 1.0 CG A:HIS37 4.1 40.1 1.0 CA A:CYS33 4.5 49.8 1.0 CA A:CYS18 4.6 33.2 1.0 CB A:TYR21 4.6 26.5 1.0 CA A:CYS27 4.6 31.4 1.0 O A:ARG35 4.7 41.2 1.0 O A:GLY30 4.8 48.9 1.0 CB A:ARG35 4.9 41.5 1.0 N A:TYR21 4.9 23.3 1.0 ND1 A:HIS29 5.0 41.0 1.0 CB A:HIS29 5.0 41.0 1.0

Zinc binding site 2 out of 2 in the Structure of Yeast U2AF Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Structure of Yeast U2AF Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn302 b:24.9 occ:1.00 NE2 A:HIS167 2.1 23.6 1.0 SG A:CYS149 2.2 24.8 1.0 SG A:CYS163 2.3 24.1 1.0 SG A:CYS157 2.3 27.1 1.0 CB A:CYS157 3.0 36.1 1.0 CD2 A:HIS167 3.0 26.5 1.0 CE1 A:HIS167 3.1 28.4 1.0 CB A:CYS149 3.2 24.6 1.0 CB A:CYS163 3.2 25.3 1.0 O A:HOH431 4.1 40.5 1.0 CG A:HIS167 4.2 25.7 1.0 ND1 A:HIS167 4.2 28.1 1.0 O A:HOH434 4.2 32.1 1.0 CA A:CYS157 4.5 43.3 1.0 CB A:HIS152 4.6 29.4 1.0 CA A:CYS149 4.6 28.9 1.0 CA A:CYS163 4.6 30.3 1.0 O A:PHE165 4.8 23.2 1.0 N A:HIS152 4.9 33.2 1.0

H.Yoshida, S.Y.Park, T.Oda, T.Akiyoshi, M.Sato, M.Shirouzu, K.Tsuda, K.Kuwasako, S.Unzai, Y.Muto, T.Urano, E.Obayashi. A Novel 3' Splice Site Recognition By the Two Zinc Fingers in the U2AF Small Subunit. Genes Dev. V. 29 1649 2015.
ISSN: ISSN 0890-9369
PubMed: 26215567
DOI: 10.1101/GAD.267104.115