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Zinc in PDB 4uf0: Crystal Structure of Jmjc Domain of Human Histone Demethylase Uty in Complex with Epitherapuetic Compound 2-(((2-((2-(Dimethylamino)Ethyl)(Ethyl)Amino)-2-Oxoethyl) Amino)Methyl)Isonicotinic Acid.Protein crystallography data
The structure of Crystal Structure of Jmjc Domain of Human Histone Demethylase Uty in Complex with Epitherapuetic Compound 2-(((2-((2-(Dimethylamino)Ethyl)(Ethyl)Amino)-2-Oxoethyl) Amino)Methyl)Isonicotinic Acid., PDB code: 4uf0
was solved by
V.Srikannathasan,
C.Johansson,
C.Gileadi,
K.Tobias,
J.Kopec,
F.Von Delft,
C.H.Arrowsmith,
C.Bountra,
A.Edwards,
U.Oppermann,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4uf0:
The structure of Crystal Structure of Jmjc Domain of Human Histone Demethylase Uty in Complex with Epitherapuetic Compound 2-(((2-((2-(Dimethylamino)Ethyl)(Ethyl)Amino)-2-Oxoethyl) Amino)Methyl)Isonicotinic Acid. also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Crystal Structure of Jmjc Domain of Human Histone Demethylase Uty in Complex with Epitherapuetic Compound 2-(((2-((2-(Dimethylamino)Ethyl)(Ethyl)Amino)-2-Oxoethyl) Amino)Methyl)Isonicotinic Acid.
(pdb code 4uf0). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Jmjc Domain of Human Histone Demethylase Uty in Complex with Epitherapuetic Compound 2-(((2-((2-(Dimethylamino)Ethyl)(Ethyl)Amino)-2-Oxoethyl) Amino)Methyl)Isonicotinic Acid., PDB code: 4uf0: Jump to Zinc binding site number: 1; 2; Zinc binding site 1 out of 2 in 4uf0Go back to Zinc Binding Sites List in 4uf0
Zinc binding site 1 out
of 2 in the Crystal Structure of Jmjc Domain of Human Histone Demethylase Uty in Complex with Epitherapuetic Compound 2-(((2-((2-(Dimethylamino)Ethyl)(Ethyl)Amino)-2-Oxoethyl) Amino)Methyl)Isonicotinic Acid.
Mono view Stereo pair view
Zinc binding site 2 out of 2 in 4uf0Go back to Zinc Binding Sites List in 4uf0
Zinc binding site 2 out
of 2 in the Crystal Structure of Jmjc Domain of Human Histone Demethylase Uty in Complex with Epitherapuetic Compound 2-(((2-((2-(Dimethylamino)Ethyl)(Ethyl)Amino)-2-Oxoethyl) Amino)Methyl)Isonicotinic Acid.
Mono view Stereo pair view
Reference:
V.Srikannathasan,
C.Johansson,
C.Gileadi,
K.Tobias,
J.Kopec,
F.Von Delft,
C.H.Arrowsmith,
C.Bountra,
A.Edwards,
U.Oppermann.
Crystal Structure of Jmjc Domain of Human Histone Demethylase Uty in Complex with Epitherapuetic Compound 2-(((2-((2-(Dimethylamino)Ethyl)(Ethyl) Amino)-2-Oxoethyl)Amino)Methyl)Isonicotinic Acid. To Be Published.
Page generated: Wed Dec 16 05:48:33 2020
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