Zinc in PDB 4u5g: Crystal Structure of Con-Ikot-Ikot Toxin

The structure of Crystal Structure of Con-Ikot-Ikot Toxin, PDB code: 4u5g was solved by L.Chen, E.Gouaux, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	19.83 / 2.20
Space group	P 31 2 1
Cell size a, b, c (Å), α, β, γ (°)	56.499, 56.499, 86.782, 90.00, 90.00, 120.00
R / Rfree (%)	20.2 / 23.9

The binding sites of Zinc atom in the Crystal Structure of Con-Ikot-Ikot Toxin (pdb code 4u5g). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Con-Ikot-Ikot Toxin, PDB code: 4u5g:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of Con-Ikot-Ikot Toxin


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Con-Ikot-Ikot Toxin within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn101 b:39.6 occ:0.96 OD2 A:ASP15 1.9 46.8 1.0 OE2 A:GLU19 2.2 52.0 1.0 CG A:ASP15 2.7 50.2 1.0 OD1 A:ASP15 2.9 52.4 1.0 CD A:GLU19 2.9 50.0 1.0 OE1 A:GLU19 3.1 48.6 1.0 CB A:ASP15 4.1 46.0 1.0 CG A:GLU19 4.2 48.2 1.0 NE A:ARG16 4.6 59.7 1.0 CZ A:ARG16 4.8 55.8 1.0 NH2 A:ARG16 5.0 51.3 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of Con-Ikot-Ikot Toxin


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Con-Ikot-Ikot Toxin within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn102 b:29.0 occ:0.57 OE2 A:GLU74 2.3 53.2 1.0 ND1 A:HIS73 2.3 51.4 1.0 OE1 A:GLU74 2.6 53.6 1.0 CD A:GLU74 2.8 55.6 1.0 CG A:HIS73 3.2 48.9 1.0 CE1 A:HIS73 3.3 47.2 1.0 CB A:HIS73 3.4 47.6 1.0 CG A:GLU74 4.3 61.7 1.0 ND2 A:ASN18 4.3 54.7 1.0 N A:GLU74 4.3 51.5 1.0 CD2 A:HIS73 4.4 44.1 1.0 NE2 A:HIS73 4.4 45.5 1.0 O A:SER70 4.4 66.6 1.0 C A:HIS73 4.6 41.5 1.0 CA A:HIS73 4.6 44.5 1.0 NZ A:LYS77 4.8 39.7 1.0 OG A:SER70 4.8 77.8 1.0 CG A:ASN18 4.9 52.9 1.0 CA A:GLU74 4.9 53.4 1.0 OD1 A:ASN18 4.9 52.4 1.0 CA A:SER70 5.0 69.1 1.0

L.Chen, K.L.Durr, E.Gouaux. X-Ray Structures of Ampa Receptor-Cone Snail Toxin Complexes Illuminate Activation Mechanism. Science V. 345 1021 2014.
ISSN: ESSN 1095-9203
PubMed: 25103405
DOI: 10.1126/SCIENCE.1258409