Atomistry » Zinc » PDB 4rld-4rvg » 4rpu
Atomistry »
  Zinc »
    PDB 4rld-4rvg »
      4rpu »

Zinc in PDB 4rpu: Crystal Structure of Human Presequence Protease in Complex with Inhibitor Mitoblock-60

Protein crystallography data

The structure of Crystal Structure of Human Presequence Protease in Complex with Inhibitor Mitoblock-60, PDB code: 4rpu was solved by S.M.Mo, W.G.Liang, J.V.King, J.Wijaya, C.M.Koehler, W.J.Tang, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 44.85 / 2.27
Space group C 1 2 1
Cell size a, b, c (Å), α, β, γ (°) 245.624, 85.490, 158.214, 90.00, 127.53, 90.00
R / Rfree (%) 17.5 / 20.8

Other elements in 4rpu:

The structure of Crystal Structure of Human Presequence Protease in Complex with Inhibitor Mitoblock-60 also contains other interesting chemical elements:

Arsenic (As) 2 atoms
Calcium (Ca) 2 atoms

Zinc Binding Sites:

The binding sites of Zinc atom in the Crystal Structure of Human Presequence Protease in Complex with Inhibitor Mitoblock-60 (pdb code 4rpu). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Human Presequence Protease in Complex with Inhibitor Mitoblock-60, PDB code: 4rpu:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in 4rpu

Go back to Zinc Binding Sites List in 4rpu
Zinc binding site 1 out of 2 in the Crystal Structure of Human Presequence Protease in Complex with Inhibitor Mitoblock-60


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Human Presequence Protease in Complex with Inhibitor Mitoblock-60 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn1101

b:38.8
occ:1.00
NE2 A:HIS104 2.0 28.4 1.0
O A:ACT1117 2.1 46.8 1.0
NE2 A:HIS108 2.1 37.6 1.0
OE1 A:GLU205 2.2 44.5 1.0
OXT A:ACT1117 2.3 44.0 1.0
OE2 A:GLU205 2.4 43.2 1.0
C A:ACT1117 2.6 37.2 1.0
CD A:GLU205 2.6 28.1 1.0
CE1 A:HIS104 2.9 28.5 1.0
CE1 A:HIS108 3.0 33.2 1.0
CD2 A:HIS104 3.1 28.5 1.0
CD2 A:HIS108 3.1 28.2 1.0
CH3 A:ACT1117 4.0 28.2 1.0
ND1 A:HIS104 4.1 28.8 1.0
CG A:GLU205 4.1 28.2 1.0
ND1 A:HIS108 4.2 28.4 1.0
CG A:HIS104 4.2 29.9 1.0
CE1 A:TYR906 4.2 27.7 1.0
CG A:HIS108 4.2 28.2 1.0
O A:HOH1573 4.3 57.6 1.0
OH A:TYR906 4.3 34.8 1.0
CG2 A:VAL202 4.4 28.6 1.0
O3 A:GOL1112 4.4 32.2 1.0
C2 A:GOL1112 4.5 50.5 1.0
CZ A:TYR906 4.7 30.7 1.0
O2 A:GOL1106 4.7 64.6 1.0
NE2 A:GLN107 4.7 29.7 1.0
CB A:GLU205 4.9 28.4 1.0
C3 A:GOL1112 4.9 46.1 1.0
OE1 A:GLN107 5.0 39.5 1.0

Zinc binding site 2 out of 2 in 4rpu

Go back to Zinc Binding Sites List in 4rpu
Zinc binding site 2 out of 2 in the Crystal Structure of Human Presequence Protease in Complex with Inhibitor Mitoblock-60


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Human Presequence Protease in Complex with Inhibitor Mitoblock-60 within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Zn1101

b:42.4
occ:1.00
OXT B:ACT1115 2.1 43.7 1.0
NE2 B:HIS108 2.1 42.3 1.0
NE2 B:HIS104 2.1 28.5 1.0
OE1 B:GLU205 2.2 44.3 1.0
O B:ACT1115 2.2 46.0 1.0
OE2 B:GLU205 2.3 39.2 1.0
C B:ACT1115 2.5 42.6 1.0
CD B:GLU205 2.6 36.5 1.0
CE1 B:HIS108 3.0 35.2 1.0
CD2 B:HIS104 3.1 28.6 1.0
CE1 B:HIS104 3.1 28.7 1.0
CD2 B:HIS108 3.1 28.2 1.0
CH3 B:ACT1115 4.0 28.1 1.0
CE1 B:TYR906 4.1 28.3 1.0
CG B:GLU205 4.1 35.3 1.0
C3 B:GOL1109 4.2 40.2 1.0
ND1 B:HIS108 4.2 28.0 1.0
ND1 B:HIS104 4.2 28.8 1.0
CG B:HIS104 4.2 28.8 1.0
CG B:HIS108 4.3 35.4 1.0
OH B:TYR906 4.3 37.1 1.0
O3 B:GOL1109 4.3 28.4 1.0
CG2 B:VAL202 4.4 28.6 1.0
CZ B:TYR906 4.6 33.8 1.0
O2 B:GOL1109 4.7 52.1 1.0
OE1 B:GLN107 4.7 36.6 1.0
O1 B:GOL1106 4.8 61.0 1.0
O3 B:GOL1106 4.8 57.1 1.0
NE2 B:GLN107 4.8 28.3 1.0
CB B:GLU205 4.8 28.7 1.0

Reference:

S.M.Mo, W.G.Liang, J.V.King, J.Wijaya, C.M.Koehler, W.J.Tang. Crystal Structure of Human Presequence Protease in Complex with Inhibitor Mitoblock-60 To Be Published.
Page generated: Sun Oct 27 07:21:03 2024

Last articles

Zn in 9FD2
Zn in 9GUW
Zn in 9GUX
Zn in 9F7C
Zn in 9GUR
Zn in 9F7A
Zn in 9DDE
Zn in 9DBY
Zn in 9EBZ
Zn in 9DGG
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy