Zinc in PDB 5jaj: Structure of Chicken LGP2 Witha 5'P 10-Mer Dsrna and Adp-ALF4-Mg.

The structure of Structure of Chicken LGP2 Witha 5'P 10-Mer Dsrna and Adp-ALF4-Mg., PDB code: 5jaj was solved by S.Cusack, E.Uchikawa, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	76.08 / 1.50
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	69.590, 97.050, 122.520, 90.00, 90.00, 90.00
R / Rfree (%)	13.3 / 16.8

The structure of Structure of Chicken LGP2 Witha 5'P 10-Mer Dsrna and Adp-ALF4-Mg. also contains other interesting chemical elements:

Fluorine	(F)	7 atoms
Magnesium	(Mg)	2 atoms
Aluminium	(Al)	1 atom

The binding sites of Zinc atom in the Structure of Chicken LGP2 Witha 5'P 10-Mer Dsrna and Adp-ALF4-Mg. (pdb code 5jaj). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Structure of Chicken LGP2 Witha 5'P 10-Mer Dsrna and Adp-ALF4-Mg., PDB code: 5jaj:

Zinc binding site 1 out of 1 in the Structure of Chicken LGP2 Witha 5'P 10-Mer Dsrna and Adp-ALF4-Mg.


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of Chicken LGP2 Witha 5'P 10-Mer Dsrna and Adp-ALF4-Mg. within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn701 b:24.0 occ:1.00 SG A:CYS613 2.3 27.3 1.0 SG A:CYS557 2.3 24.8 1.0 SG A:CYS554 2.3 22.6 1.0 SG A:CYS610 2.4 23.7 1.0 CB A:CYS610 3.2 22.8 1.0 CB A:CYS554 3.2 20.2 1.0 CB A:CYS557 3.3 25.1 1.0 CB A:CYS613 3.3 27.9 1.0 N A:CYS557 3.8 27.1 1.0 N A:CYS613 3.9 31.2 1.0 CA A:CYS557 4.1 27.3 1.0 CA A:CYS613 4.2 31.0 1.0 CG1 A:VAL559 4.3 21.8 1.0 CB A:GLN615 4.4 26.5 1.0 CB A:GLU612 4.4 30.0 0.5 CB A:GLU612 4.6 34.8 0.5 CA A:CYS554 4.6 18.4 1.0 CA A:CYS610 4.6 23.5 1.0 CB A:ASN556 4.7 28.7 1.0 C A:GLU612 4.8 31.1 0.5 C A:CYS613 4.8 29.0 1.0 C A:ASN556 4.8 26.4 1.0 NE1 A:TRP617 4.8 25.0 1.0 CZ2 A:TRP617 4.9 22.6 1.0 C A:CYS557 4.9 23.6 1.0 C A:GLU612 4.9 30.8 0.5 N A:GLN615 5.0 28.7 1.0

E.Uchikawa, M.Lethier, H.Malet, J.Brunel, D.Gerlier, S.Cusack. Structural Analysis of Dsrna Binding to Anti-Viral Pattern Recognition Receptors LGP2 and MDA5. Mol.Cell V. 62 586 2016.
ISSN: ISSN 1097-2765
PubMed: 27203181
DOI: 10.1016/J.MOLCEL.2016.04.021