Zinc in PDB 4rf0: Crystal Structure of the Middle-East Respiratory Syndrome Coronavirus Papain-Like Protease in Complex with Ubiquitin (Space Group P6522)

The structure of Crystal Structure of the Middle-East Respiratory Syndrome Coronavirus Papain-Like Protease in Complex with Ubiquitin (Space Group P6522), PDB code: 4rf0 was solved by B.A.Bailey-Elkin, G.G.Johnson, B.L.Mark, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	44.24 / 2.80
Space group	P 65 2 2
Cell size a, b, c (Å), α, β, γ (°)	176.972, 176.972, 84.549, 90.00, 90.00, 120.00
R / Rfree (%)	24 / 28.1

The binding sites of Zinc atom in the Crystal Structure of the Middle-East Respiratory Syndrome Coronavirus Papain-Like Protease in Complex with Ubiquitin (Space Group P6522) (pdb code 4rf0). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of the Middle-East Respiratory Syndrome Coronavirus Papain-Like Protease in Complex with Ubiquitin (Space Group P6522), PDB code: 4rf0:

Zinc binding site 1 out of 1 in the Crystal Structure of the Middle-East Respiratory Syndrome Coronavirus Papain-Like Protease in Complex with Ubiquitin (Space Group P6522)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of the Middle-East Respiratory Syndrome Coronavirus Papain-Like Protease in Complex with Ubiquitin (Space Group P6522) within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1901 b:88.9 occ:1.00 SG A:CYS1675 2.3 67.9 1.0 SG A:CYS1672 2.3 63.5 1.0 SG A:CYS1709 2.3 62.5 1.0 SG A:CYS1707 2.3 68.9 1.0 CB A:CYS1707 3.1 70.0 1.0 CB A:CYS1675 3.4 62.5 1.0 CB A:CYS1672 3.4 75.0 1.0 CB A:CYS1709 3.8 62.3 1.0 N A:CYS1675 3.9 69.0 1.0 CA A:CYS1675 4.2 66.9 1.0 CB A:VAL1674 4.4 54.4 1.0 NH1 A:ARG1713 4.4 56.3 1.0 N A:CYS1709 4.4 85.4 1.0 CA A:CYS1707 4.6 60.5 1.0 CA A:CYS1709 4.7 72.9 1.0 CA A:CYS1672 4.8 61.8 1.0 C A:VAL1674 4.8 57.8 1.0 N A:GLN1708 4.9 75.8 1.0 CG1 A:VAL1674 4.9 43.9 1.0 C A:CYS1707 4.9 73.8 1.0 CA A:VAL1674 5.0 67.5 1.0

B.A.Bailey-Elkin, R.C.Knaap, G.G.Johnson, T.J.Dalebout, D.K.Ninaber, P.B.Van Kasteren, P.J.Bredenbeek, E.J.Snijder, M.Kikkert, B.L.Mark. Crystal Structure of the Mers Coronavirus Papain-Like Protease Bound to Ubiquitin Facilitates Targeted Disruption of Deubiquitinating Activity to Demonstrate Its Role in Innate Immune Suppression. J.Biol.Chem. 2014.
ISSN: ESSN 1083-351X
PubMed: 25320088
DOI: 10.1074/JBC.M114.609644