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Atomistry » Zinc » PDB 4ntn-4o6o » 4nxo | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Zinc » PDB 4ntn-4o6o » 4nxo » |
Zinc in PDB 4nxo: Crystal Structure of Insulin Degrading Enzyme in Complex with BDM44768Enzymatic activity of Crystal Structure of Insulin Degrading Enzyme in Complex with BDM44768
All present enzymatic activity of Crystal Structure of Insulin Degrading Enzyme in Complex with BDM44768:
3.4.24.56; Protein crystallography data
The structure of Crystal Structure of Insulin Degrading Enzyme in Complex with BDM44768, PDB code: 4nxo
was solved by
W.G.Liang,
R.Deprez,
B.Deprez,
W.Tang,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4nxo:
The structure of Crystal Structure of Insulin Degrading Enzyme in Complex with BDM44768 also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Crystal Structure of Insulin Degrading Enzyme in Complex with BDM44768
(pdb code 4nxo). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Insulin Degrading Enzyme in Complex with BDM44768, PDB code: 4nxo: Jump to Zinc binding site number: 1; 2; Zinc binding site 1 out of 2 in 4nxoGo back to Zinc Binding Sites List in 4nxo
Zinc binding site 1 out
of 2 in the Crystal Structure of Insulin Degrading Enzyme in Complex with BDM44768
Mono view Stereo pair view
Zinc binding site 2 out of 2 in 4nxoGo back to Zinc Binding Sites List in 4nxo
Zinc binding site 2 out
of 2 in the Crystal Structure of Insulin Degrading Enzyme in Complex with BDM44768
Mono view Stereo pair view
Reference:
R.Deprez-Poulain,
N.Hennuyer,
D.Bosc,
W.G.Liang,
E.Enee,
X.Marechal,
J.Charton,
J.Totobenazara,
G.Berte,
J.Jahklal,
T.Verdelet,
J.Dumont,
S.Dassonneville,
E.Woitrain,
M.Gauriot,
C.Paquet,
I.Duplan,
P.Hermant,
F.X.Cantrelle,
E.Sevin,
M.Culot,
V.Landry,
A.Herledan,
C.Piveteau,
G.Lippens,
F.Leroux,
W.J.Tang,
P.Van Endert,
B.Staels,
B.Deprez.
Catalytic Site Inhibition of Insulin-Degrading Enzyme By A Small Molecule Induces Glucose Intolerance in Mice. Nat Commun V. 6 8250 2015.
Page generated: Wed Dec 16 05:37:51 2020
ISSN: ESSN 2041-1723 PubMed: 26394692 DOI: 10.1038/NCOMMS9250 |
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