Zinc in PDB 4nxc: Sperm Whale Myoglobin Under 30 Bar Nitrous Oxide

The structure of Sperm Whale Myoglobin Under 30 Bar Nitrous Oxide, PDB code: 4nxc was solved by N.Colloc'h, T.Prange, B.Vallone, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 1.55
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	35.449, 30.545, 63.634, 90.00, 104.57, 90.00
R / Rfree (%)	19 / 22.5

The structure of Sperm Whale Myoglobin Under 30 Bar Nitrous Oxide also contains other interesting chemical elements:

Iron

(Fe)

1 atom

The binding sites of Zinc atom in the Sperm Whale Myoglobin Under 30 Bar Nitrous Oxide (pdb code 4nxc). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Sperm Whale Myoglobin Under 30 Bar Nitrous Oxide, PDB code: 4nxc:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Sperm Whale Myoglobin Under 30 Bar Nitrous Oxide


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Sperm Whale Myoglobin Under 30 Bar Nitrous Oxide within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn202 b:21.3 occ:0.90 OE2 A:GLU38 1.8 24.8 1.0 ND1 A:HIS36 2.0 19.8 1.0 CD A:GLU38 2.7 22.6 1.0 OE1 A:GLU38 2.8 23.6 1.0 CE1 A:HIS36 2.9 23.6 1.0 CG A:HIS36 3.1 21.1 1.0 CB A:HIS36 3.5 19.1 1.0 CA A:HIS36 3.7 19.3 1.0 NE2 A:HIS36 4.1 23.7 1.0 O A:SER35 4.1 22.6 1.0 CG A:GLU38 4.1 23.6 1.0 CE2 A:PHE106 4.1 22.2 1.0 CD2 A:HIS36 4.2 21.2 1.0 CZ A:PHE106 4.3 21.6 1.0 C A:HIS36 4.6 19.5 1.0 N A:HIS36 4.7 18.7 1.0 C A:SER35 4.8 20.1 1.0 CD2 A:PHE106 4.8 20.0 1.0 CD A:PRO37 5.0 19.8 1.0

Zinc binding site 2 out of 2 in the Sperm Whale Myoglobin Under 30 Bar Nitrous Oxide


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Sperm Whale Myoglobin Under 30 Bar Nitrous Oxide within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn203 b:22.7 occ:0.90 OE2 A:GLU59 1.9 24.5 1.0 NZ A:LYS62 2.1 21.0 1.0 CD A:GLU59 2.6 19.8 1.0 OE1 A:GLU59 2.7 22.7 1.0 CE A:LYS62 3.1 20.7 1.0 O A:HOH352 3.8 38.5 1.0 CG A:GLU59 4.1 21.3 1.0 CD A:LYS62 4.4 20.2 1.0

J.H.Abraini, G.Marassio, H.N.David, B.Vallone, T.Prange, N.Colloc'h. Crystallographic Studies with Xenon and Nitrous Oxide Provide Evidence For Protein-Dependent Processes in the Mechanisms of General Anesthesia Anesthesiology 2014.
ISSN: ESSN 1528-1175
PubMed: 25211169
DOI: 10.1097/ALN.0000000000000435