Zinc in PDB 4n4h: Crystal Structure of the Bromo-Pwwp of the Mouse Zinc Finger Mynd-Type Containing 11 Isoform Alpha in Complex with Histone H3.1K36ME3

The structure of Crystal Structure of the Bromo-Pwwp of the Mouse Zinc Finger Mynd-Type Containing 11 Isoform Alpha in Complex with Histone H3.1K36ME3, PDB code: 4n4h was solved by Y.Li, Y.Ren, H.Li, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	36.48 / 2.30
Space group	P 43 21 2
Cell size a, b, c (Å), α, β, γ (°)	64.358, 64.358, 122.059, 90.00, 90.00, 90.00
R / Rfree (%)	20.6 / 26.3

The binding sites of Zinc atom in the Crystal Structure of the Bromo-Pwwp of the Mouse Zinc Finger Mynd-Type Containing 11 Isoform Alpha in Complex with Histone H3.1K36ME3 (pdb code 4n4h). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of the Bromo-Pwwp of the Mouse Zinc Finger Mynd-Type Containing 11 Isoform Alpha in Complex with Histone H3.1K36ME3, PDB code: 4n4h:

Zinc binding site 1 out of 1 in the Crystal Structure of the Bromo-Pwwp of the Mouse Zinc Finger Mynd-Type Containing 11 Isoform Alpha in Complex with Histone H3.1K36ME3


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of the Bromo-Pwwp of the Mouse Zinc Finger Mynd-Type Containing 11 Isoform Alpha in Complex with Histone H3.1K36ME3 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn401 b:31.1 occ:1.00 NE2 A:HIS281 2.0 33.2 1.0 SG A:CYS258 2.3 24.9 1.0 SG A:CYS261 2.3 28.1 1.0 SG A:CYS277 2.4 27.8 1.0 CD2 A:HIS281 2.9 26.7 1.0 CE1 A:HIS281 3.1 30.8 1.0 CB A:CYS277 3.2 25.1 1.0 CB A:CYS261 3.3 29.6 1.0 CB A:CYS258 3.3 25.6 1.0 N A:CYS261 3.6 23.8 1.0 CA A:CYS261 3.9 22.7 1.0 O A:HOH517 4.0 32.3 1.0 CG A:HIS281 4.1 27.1 1.0 ND1 A:HIS281 4.1 26.7 1.0 O A:HOH512 4.4 21.1 1.0 C A:ASN260 4.6 25.6 1.0 O A:HOH514 4.7 28.1 1.0 CB A:ASN260 4.7 27.2 1.0 CA A:CYS277 4.7 26.8 1.0 CA A:CYS258 4.7 27.4 1.0 CE A:MET299 4.8 21.1 1.0

H.Wen, Y.Li, Y.Xi, S.Jiang, S.Stratton, D.Peng, K.Tanaka, Y.Ren, Z.Xia, J.Wu, B.Li, M.C.Barton, W.Li, H.Li, X.Shi. ZMYND11 Links Histone H3.3K36ME3 to Transcription Elongation and Tumour Suppression Nature V. 508 263 2014.
ISSN: ISSN 0028-0836
PubMed: 24590075
DOI: 10.1038/NATURE13045