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Zinc in PDB 4mex: Crystal Structure of Escherichia Coli Rna Polymerase in Complex with Salinamide A
Enzymatic activity of Crystal Structure of Escherichia Coli Rna Polymerase in Complex with Salinamide A
All present enzymatic activity of Crystal Structure of Escherichia Coli Rna Polymerase in Complex with Salinamide A:
2.7.7.6;
2.7.7.6;
Protein crystallography data
The structure of Crystal Structure of Escherichia Coli Rna Polymerase in Complex with Salinamide A, PDB code: 4mex
was solved by
Y.Feng,
Y.Zhang,
E.Arnold,
R.H.Ebright,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 49.87 / 3.90 |
| Space group | P 21 21 21 |
| Cell size a, b, c (Å), α, β, γ (°) | 185.800, 208.188, 308.179, 90.00, 90.00, 90.00 |
| R / Rfree (%) | 28.6 / 32.5 |
Other elements in 4mex:
The structure of Crystal Structure of Escherichia Coli Rna Polymerase in Complex with Salinamide A also contains other interesting chemical elements:
| Magnesium | (Mg) | 2 atoms |
Zinc Binding Sites:
The binding sites of Zinc atom in the Crystal Structure of Escherichia Coli Rna Polymerase in Complex with Salinamide A
(pdb code 4mex). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 4 binding sites of Zinc where determined in the Crystal Structure of Escherichia Coli Rna Polymerase in Complex with Salinamide A, PDB code: 4mex:
Jump to Zinc binding site number: 1; 2; 3; 4;
In total 4 binding sites of Zinc where determined in the Crystal Structure of Escherichia Coli Rna Polymerase in Complex with Salinamide A, PDB code: 4mex:
Jump to Zinc binding site number: 1; 2; 3; 4;
Zinc binding site 1 out of 4 in 4mex
Go back to
Zinc Binding Sites List in 4mex
Zinc binding site 1 out
of 4 in the Crystal Structure of Escherichia Coli Rna Polymerase in Complex with Salinamide A
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Zinc with other atoms in the Zn binding
site number 1 of Crystal Structure of Escherichia Coli Rna Polymerase in Complex with Salinamide A within 5.0Å range:
|
Zinc binding site 2 out of 4 in 4mex
Go back to
Zinc Binding Sites List in 4mex
Zinc binding site 2 out
of 4 in the Crystal Structure of Escherichia Coli Rna Polymerase in Complex with Salinamide A
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Zinc with other atoms in the Zn binding
site number 2 of Crystal Structure of Escherichia Coli Rna Polymerase in Complex with Salinamide A within 5.0Å range:
|
Zinc binding site 3 out of 4 in 4mex
Go back to
Zinc Binding Sites List in 4mex
Zinc binding site 3 out
of 4 in the Crystal Structure of Escherichia Coli Rna Polymerase in Complex with Salinamide A
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Zinc with other atoms in the Zn binding
site number 3 of Crystal Structure of Escherichia Coli Rna Polymerase in Complex with Salinamide A within 5.0Å range:
|
Zinc binding site 4 out of 4 in 4mex
Go back to
Zinc Binding Sites List in 4mex
Zinc binding site 4 out
of 4 in the Crystal Structure of Escherichia Coli Rna Polymerase in Complex with Salinamide A
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Zinc with other atoms in the Zn binding
site number 4 of Crystal Structure of Escherichia Coli Rna Polymerase in Complex with Salinamide A within 5.0Å range:
|
Reference:
D.Degen,
Y.Feng,
Y.Zhang,
K.Y.Ebright,
Y.W.Ebright,
M.Gigliotti,
H.Vahedian-Movahed,
S.Mandal,
M.Talaue,
N.Connell,
E.Arnold,
W.Fenical,
R.H.Ebright.
Transcription Inhibition By the Depsipeptide Antibiotic Salinamide A. Elife V. 3 02451 2014.
ISSN: ESSN 2050-084X
PubMed: 24843001
DOI: 10.7554/ELIFE.02451
Page generated: Sun Oct 27 02:24:16 2024
ISSN: ESSN 2050-084X
PubMed: 24843001
DOI: 10.7554/ELIFE.02451
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