Zinc in PDB 4jqp: X-Ray Crystal Structure of A 4-Hydroxythreonine-4-Phosphate Dehydrogenase From Burkholderia Phymatum

All present enzymatic activity of X-Ray Crystal Structure of A 4-Hydroxythreonine-4-Phosphate Dehydrogenase From Burkholderia Phymatum:
1.1.1.262;

The structure of X-Ray Crystal Structure of A 4-Hydroxythreonine-4-Phosphate Dehydrogenase From Burkholderia Phymatum, PDB code: 4jqp was solved by Seattle Structural Genomics Center For Infectious Disease (Ssgcid), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	48.91 / 1.65
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	48.980, 99.280, 71.030, 90.00, 93.92, 90.00
R / Rfree (%)	14.8 / 17.4

The structure of X-Ray Crystal Structure of A 4-Hydroxythreonine-4-Phosphate Dehydrogenase From Burkholderia Phymatum also contains other interesting chemical elements:

Magnesium	(Mg)	2 atoms
Calcium	(Ca)	2 atoms

The binding sites of Zinc atom in the X-Ray Crystal Structure of A 4-Hydroxythreonine-4-Phosphate Dehydrogenase From Burkholderia Phymatum (pdb code 4jqp). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the X-Ray Crystal Structure of A 4-Hydroxythreonine-4-Phosphate Dehydrogenase From Burkholderia Phymatum, PDB code: 4jqp:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the X-Ray Crystal Structure of A 4-Hydroxythreonine-4-Phosphate Dehydrogenase From Burkholderia Phymatum


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of X-Ray Crystal Structure of A 4-Hydroxythreonine-4-Phosphate Dehydrogenase From Burkholderia Phymatum within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn401 b:13.3 occ:0.75 O A:HOH753 2.0 14.7 1.0 O A:HOH644 2.1 18.1 1.0 O A:HOH698 2.2 20.1 1.0 NE2 A:HIS180 2.2 16.9 1.0 NE2 B:HIS224 2.2 16.9 1.0 NE2 A:HIS280 2.3 9.9 1.0 CE1 B:HIS224 3.1 17.9 1.0 CD2 A:HIS180 3.1 16.5 1.0 CE1 A:HIS180 3.2 17.2 1.0 CD2 A:HIS280 3.2 9.9 1.0 CE1 A:HIS280 3.2 9.9 1.0 CD2 B:HIS224 3.3 16.3 1.0 O A:HOH867 3.9 32.8 1.0 O A:HOH892 4.0 49.7 1.0 NE2 A:HIS284 4.0 12.1 1.0 O B:HOH801 4.1 29.8 1.0 ND1 B:HIS224 4.2 17.9 1.0 CD2 A:HIS284 4.3 12.2 1.0 O A:HOH757 4.3 31.3 1.0 CG A:HIS180 4.3 15.2 1.0 ND1 A:HIS180 4.3 16.9 1.0 ND1 A:HIS280 4.3 9.6 1.0 CG B:HIS224 4.4 15.8 1.0 CG A:HIS280 4.4 9.4 1.0

Zinc binding site 2 out of 2 in the X-Ray Crystal Structure of A 4-Hydroxythreonine-4-Phosphate Dehydrogenase From Burkholderia Phymatum


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of X-Ray Crystal Structure of A 4-Hydroxythreonine-4-Phosphate Dehydrogenase From Burkholderia Phymatum within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn401 b:13.8 occ:0.76 O A:HOH704 2.1 18.5 1.0 O B:HOH562 2.1 16.5 1.0 O B:HOH651 2.1 17.7 1.0 NE2 B:HIS180 2.2 15.1 1.0 NE2 A:HIS224 2.2 15.6 1.0 NE2 B:HIS280 2.3 10.8 1.0 CE1 A:HIS224 3.0 16.5 1.0 CD2 B:HIS180 3.1 13.6 1.0 CE1 B:HIS180 3.2 14.4 1.0 CD2 B:HIS280 3.2 10.7 1.0 CE1 B:HIS280 3.2 10.8 1.0 CD2 A:HIS224 3.2 14.6 1.0 NE2 B:HIS284 4.1 10.7 1.0 O A:HOH653 4.2 23.1 1.0 ND1 A:HIS224 4.2 16.2 1.0 CD2 B:HIS284 4.3 10.5 1.0 ND1 B:HIS180 4.3 14.5 1.0 CG B:HIS180 4.3 13.3 1.0 ND1 B:HIS280 4.3 10.6 1.0 CG A:HIS224 4.3 14.0 1.0 CG B:HIS280 4.4 10.3 1.0 O A:HOH786 4.5 44.4 1.0 O B:HOH770 4.6 33.0 1.0

J.W.Fairman, M.C.Clifton, T.E.Edwards, D.Lorimer. X-Ray Crystal Structure of A 4-Hydroxythreonine-4-Phosphate Dehydrogenase From Burkholderia Phymatum To Be Published.