Zinc in PDB 4ivv: Catalytic Amidase Domain of the Major Autolysin Lyta From Streptococcus Pneumaniae

All present enzymatic activity of Catalytic Amidase Domain of the Major Autolysin Lyta From Streptococcus Pneumaniae:
3.5.1.28;

The structure of Catalytic Amidase Domain of the Major Autolysin Lyta From Streptococcus Pneumaniae, PDB code: 4ivv was solved by T.Sandalova, A.Achour, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	17.46 / 1.05
Space group	P 32
Cell size a, b, c (Å), α, β, γ (°)	50.440, 50.440, 72.610, 90.00, 90.00, 120.00
R / Rfree (%)	14.1 / 15.7

The binding sites of Zinc atom in the Catalytic Amidase Domain of the Major Autolysin Lyta From Streptococcus Pneumaniae (pdb code 4ivv). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Catalytic Amidase Domain of the Major Autolysin Lyta From Streptococcus Pneumaniae, PDB code: 4ivv:

Zinc binding site 1 out of 1 in the Catalytic Amidase Domain of the Major Autolysin Lyta From Streptococcus Pneumaniae


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Catalytic Amidase Domain of the Major Autolysin Lyta From Streptococcus Pneumaniae within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn201 b:9.9 occ:0.80 OD2 A:ASP149 2.2 8.6 1.0 ND1 A:HIS26 2.2 6.5 1.0 ND1 A:HIS133 2.2 7.9 1.0 O A:HOH384 2.5 13.8 1.0 O A:HOH301 2.5 15.2 1.0 O A:HOH423 2.6 21.5 1.0 OD1 A:ASP149 2.8 8.5 1.0 CG A:ASP149 2.8 6.8 1.0 CE1 A:HIS26 3.1 6.6 1.0 CE1 A:HIS133 3.2 7.8 1.0 CG A:HIS133 3.2 6.9 1.0 CG A:HIS26 3.3 6.7 1.0 CB A:HIS133 3.5 7.2 1.0 CB A:HIS26 3.6 6.5 1.0 NE2 A:HIS26 4.2 7.0 1.0 CA A:HIS26 4.2 6.5 1.0 NE2 A:HIS133 4.3 8.3 1.0 CB A:ASP149 4.3 7.6 1.0 CD2 A:HIS133 4.3 7.6 1.0 CD2 A:HIS26 4.3 6.3 1.0 O A:ASP73 4.4 7.6 1.0 O A:SER27 4.4 9.5 1.0 CE1 A:PHE52 4.6 6.7 0.5 O A:HOH403 4.7 22.4 1.0 N A:SER27 4.7 7.0 1.0 CB A:HIS147 4.7 8.8 1.0 CZ A:PHE52 4.9 9.5 0.5 CA A:HIS133 4.9 7.2 1.0

P.Mellroth, T.Sandalova, A.Kikhney, F.Vilaplana, D.Hesek, M.Lee, S.Mobashery, S.Normark, D.Svergun, B.Henriques-Normark, A.Achour. Structural and Functional Insights Into Peptidoglycan Access For the Lytic Amidase Lyta of Streptococcus Pneumoniae. Mbio V. 5 01120 2014.
ISSN: ESSN 2150-7511
PubMed: 24520066
DOI: 10.1128/MBIO.01120-13