Zinc in PDB 4iuq: Crystal Structure of SHH1 Sawadee Domain

The structure of Crystal Structure of SHH1 Sawadee Domain, PDB code: 4iuq was solved by J.Du, D.J.Patel, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	40.07 / 2.81
Space group	P 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	54.708, 117.691, 53.409, 90.00, 90.00, 90.00
R / Rfree (%)	20.1 / 26.1

The binding sites of Zinc atom in the Crystal Structure of SHH1 Sawadee Domain (pdb code 4iuq). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of SHH1 Sawadee Domain, PDB code: 4iuq:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of SHH1 Sawadee Domain


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of SHH1 Sawadee Domain within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn301 b:48.5 occ:1.00 SG B:CYS191 2.4 28.1 1.0 SG B:CYS230 2.4 45.7 1.0 NE2 B:HIS225 2.5 31.0 1.0 SG B:CYS232 2.6 39.0 1.0 CB B:CYS191 3.1 24.0 1.0 CD2 B:HIS225 3.1 29.1 1.0 CB B:CYS230 3.4 22.1 1.0 CB B:CYS232 3.5 27.1 1.0 CE1 B:HIS225 3.6 31.1 1.0 CA B:CYS230 4.1 33.0 1.0 NH1 B:ARG222 4.2 41.1 1.0 N B:CYS232 4.2 25.1 1.0 CG B:HIS225 4.3 23.8 1.0 CA B:CYS232 4.5 25.7 1.0 ND1 B:HIS225 4.5 30.6 1.0 CA B:CYS191 4.6 21.4 1.0 O B:PRO188 4.6 37.5 1.0 C B:CYS230 4.7 36.7 1.0 N B:ASN231 4.7 29.7 1.0 C B:CYS191 5.0 34.1 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of SHH1 Sawadee Domain


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of SHH1 Sawadee Domain within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn301 b:70.8 occ:1.00 SG A:CYS191 2.3 61.1 1.0 NE2 A:HIS225 2.4 44.2 1.0 SG A:CYS230 2.4 57.0 1.0 SG A:CYS232 2.5 54.5 1.0 CB A:CYS191 3.3 40.9 1.0 CE1 A:HIS225 3.4 39.8 1.0 CD2 A:HIS225 3.4 45.2 1.0 CB A:CYS232 3.5 43.8 1.0 CB A:CYS230 3.7 57.8 1.0 N A:CYS232 3.9 40.4 1.0 CA A:CYS232 4.3 46.2 1.0 CA A:CYS230 4.3 67.7 1.0 NH1 A:ARG222 4.4 66.7 1.0 N A:ASN231 4.4 53.2 1.0 ND1 A:HIS225 4.5 42.6 1.0 CG A:HIS225 4.5 46.1 1.0 C A:CYS230 4.7 66.0 1.0 CA A:CYS191 4.7 41.2 1.0 CD A:ARG222 4.9 52.7 1.0 O A:GLY223 4.9 70.9 1.0 C A:ASN231 5.0 37.5 1.0

J.A.Law, J.Du, C.J.Hale, S.Feng, K.Krajewski, A.M.Palanca, B.D.Strahl, D.J.Patel, S.E.Jacobsen. Polymerase IV Occupancy at Rna-Directed Dna Methylation Sites Requires SHH1. Nature V. 498 385 2013.
ISSN: ISSN 0028-0836
PubMed: 23636332
DOI: 10.1038/NATURE12178