Zinc in PDB 4ipp: Trna-Guanine-Transglycosylase (Tgt) Mutant V262D Apo-Structure

All present enzymatic activity of Trna-Guanine-Transglycosylase (Tgt) Mutant V262D Apo-Structure:
2.4.2.29;

The structure of Trna-Guanine-Transglycosylase (Tgt) Mutant V262D Apo-Structure, PDB code: 4ipp was solved by M.Neeb, A.Heine, G.Klebe, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.51 / 1.33
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	91.047, 65.099, 70.337, 90.00, 96.22, 90.00
R / Rfree (%)	13.3 / 15

The binding sites of Zinc atom in the Trna-Guanine-Transglycosylase (Tgt) Mutant V262D Apo-Structure (pdb code 4ipp). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Trna-Guanine-Transglycosylase (Tgt) Mutant V262D Apo-Structure, PDB code: 4ipp:

Zinc binding site 1 out of 1 in the Trna-Guanine-Transglycosylase (Tgt) Mutant V262D Apo-Structure


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Trna-Guanine-Transglycosylase (Tgt) Mutant V262D Apo-Structure within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn401 b:8.9 occ:1.00 ND1 A:HIS349 2.1 8.3 1.0 SG A:CYS323 2.3 9.4 1.0 SG A:CYS320 2.3 9.1 1.0 SG A:CYS318 2.3 10.3 1.0 CE1 A:HIS349 2.9 9.1 1.0 CG A:HIS349 3.2 7.9 1.0 CB A:CYS323 3.3 9.2 1.0 CB A:CYS318 3.3 10.9 1.0 CB A:CYS320 3.4 9.7 1.0 CB A:HIS349 3.7 8.2 1.0 N A:CYS323 3.9 8.9 1.0 CA A:HIS349 4.1 7.4 1.0 NE2 A:HIS349 4.1 8.5 1.0 N A:CYS320 4.2 10.1 1.0 CA A:CYS323 4.2 9.4 1.0 CA A:CYS320 4.2 10.1 1.0 CD2 A:HIS349 4.3 8.8 1.0 O A:HIS349 4.5 7.8 1.0 CA A:CYS318 4.6 9.8 1.0 O A:CYS320 4.7 10.4 1.0 C A:CYS320 4.7 9.5 1.0 C A:CYS318 4.7 10.9 1.0 CB A:VAL322 4.8 8.7 1.0 C A:HIS349 4.8 7.5 1.0 O A:CYS318 4.8 11.7 1.0 C A:VAL322 4.9 8.9 1.0

M.Neeb, L.J.Barandun, C.Hohn, A.Heine, F.Diederich, G.Klebe. Investigating the Advantage of Ligands with Residual Mobility in Binding Mutated Tgt To Be Published.