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Atomistry » Zinc » PDB 4i7d-4ih7 » 4ie6 » |
Zinc in PDB 4ie6: Crystal Structure of the Human Fat Mass and Obesity Associated Protein (Fto) in Complex with N-[(1-Chloro-4-Hydroxyisoquinolin-3-Yl) Carbonyl]Glycine (IOX3/UN9)Protein crystallography data
The structure of Crystal Structure of the Human Fat Mass and Obesity Associated Protein (Fto) in Complex with N-[(1-Chloro-4-Hydroxyisoquinolin-3-Yl) Carbonyl]Glycine (IOX3/UN9), PDB code: 4ie6
was solved by
W.S.Aik,
M.A.Mcdonough,
C.J.Schofield,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4ie6:
The structure of Crystal Structure of the Human Fat Mass and Obesity Associated Protein (Fto) in Complex with N-[(1-Chloro-4-Hydroxyisoquinolin-3-Yl) Carbonyl]Glycine (IOX3/UN9) also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Crystal Structure of the Human Fat Mass and Obesity Associated Protein (Fto) in Complex with N-[(1-Chloro-4-Hydroxyisoquinolin-3-Yl) Carbonyl]Glycine (IOX3/UN9)
(pdb code 4ie6). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of the Human Fat Mass and Obesity Associated Protein (Fto) in Complex with N-[(1-Chloro-4-Hydroxyisoquinolin-3-Yl) Carbonyl]Glycine (IOX3/UN9), PDB code: 4ie6: Zinc binding site 1 out of 1 in 4ie6Go back to Zinc Binding Sites List in 4ie6
Zinc binding site 1 out
of 1 in the Crystal Structure of the Human Fat Mass and Obesity Associated Protein (Fto) in Complex with N-[(1-Chloro-4-Hydroxyisoquinolin-3-Yl) Carbonyl]Glycine (IOX3/UN9)
Mono view Stereo pair view
Reference:
W.S.Aik,
M.Demetriades,
M.K.K.Hamdan,
E.A.L.Bagg,
K.K.Yeoh,
C.Lejeune,
Z.Zhang,
M.A.Mcdonough,
C.J.Schofield.
Structural Basis For Inhibition of the Fat Mass and Obesity Associated Protein (Fto) J.Med.Chem. V. 56 3680 2013.
Page generated: Wed Dec 16 05:23:48 2020
ISSN: ISSN 0022-2623 PubMed: 23547775 DOI: 10.1021/JM400193D |
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