Zinc in PDB 4i2x: Crystal Structure of Signal Regulatory Protein Gamma (Sirp-Gamma) in Complex with FABOX117

The structure of Crystal Structure of Signal Regulatory Protein Gamma (Sirp-Gamma) in Complex with FABOX117, PDB code: 4i2x was solved by J.E.Nettleship, J.Ren, D.I.Stuart, R.J.Owens, Oxford Protein Productionfacility (Oppf), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.82 / 2.48
Space group	P 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	140.361, 174.191, 81.734, 90.00, 90.00, 90.00
R / Rfree (%)	19.6 / 26

The structure of Crystal Structure of Signal Regulatory Protein Gamma (Sirp-Gamma) in Complex with FABOX117 also contains other interesting chemical elements:

Chlorine

(Cl)

2 atoms

The binding sites of Zinc atom in the Crystal Structure of Signal Regulatory Protein Gamma (Sirp-Gamma) in Complex with FABOX117 (pdb code 4i2x). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of Signal Regulatory Protein Gamma (Sirp-Gamma) in Complex with FABOX117, PDB code: 4i2x:

Zinc binding site 1 out of 1 in the Crystal Structure of Signal Regulatory Protein Gamma (Sirp-Gamma) in Complex with FABOX117


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Signal Regulatory Protein Gamma (Sirp-Gamma) in Complex with FABOX117 within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn301 b:68.7 occ:1.00 O B:HOH464 2.0 46.3 1.0 NE2 B:HIS224 2.0 76.1 1.0 NE2 B:HIS228 2.1 78.3 1.0 CD2 B:HIS224 2.9 71.8 1.0 CD2 B:HIS228 3.0 90.1 1.0 CE1 B:HIS224 3.0 75.1 1.0 CE1 B:HIS228 3.1 76.7 1.0 O B:HOH402 3.5 41.8 1.0 O B:HOH445 3.6 46.9 1.0 CG B:HIS224 4.1 72.0 1.0 CG B:HIS228 4.1 93.8 1.0 ND1 B:HIS224 4.1 72.4 1.0 ND1 B:HIS228 4.2 85.2 1.0

J.E.Nettleship, J.Ren, D.J.Scot, N.Rahman, D.Hatherley, Y.Zhao, D.I.Stuart, A.N.Barclay, R.J.Owens. Crystal Structure of Signal Regulatory Protein Gamma (Sirp-Gamma) in Complex with FABOX117 To Be Published.