Zinc in PDB 4hrw: Identification of Function and Mechanistic Insights of Guanine Deaminase From Nitrosomonas Europaea

The structure of Identification of Function and Mechanistic Insights of Guanine Deaminase From Nitrosomonas Europaea, PDB code: 4hrw was solved by R.Anand, A.Bitra, H.Bhukya, A.S.Tanwar, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	36.00 / 2.43
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	38.110, 73.250, 109.810, 90.00, 90.00, 90.00
R / Rfree (%)	20.6 / 26.2

The binding sites of Zinc atom in the Identification of Function and Mechanistic Insights of Guanine Deaminase From Nitrosomonas Europaea (pdb code 4hrw). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Identification of Function and Mechanistic Insights of Guanine Deaminase From Nitrosomonas Europaea, PDB code: 4hrw:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Identification of Function and Mechanistic Insights of Guanine Deaminase From Nitrosomonas Europaea


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Identification of Function and Mechanistic Insights of Guanine Deaminase From Nitrosomonas Europaea within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn201 b:22.1 occ:1.00 ND1 A:HIS77 2.2 8.5 1.0 SG A:CYS115 2.4 17.0 1.0 SG A:CYS112 2.4 17.7 1.0 CE1 A:HIS77 3.0 8.5 1.0 CB A:CYS115 3.2 17.0 1.0 CG A:HIS77 3.2 8.5 1.0 CB A:CYS112 3.4 17.7 1.0 CB A:HIS77 3.7 8.5 1.0 N A:CYS115 3.8 20.4 1.0 N A:CYS112 3.8 17.3 1.0 O A:HOH302 4.1 15.3 1.0 CA A:CYS115 4.1 20.4 1.0 NE2 A:HIS77 4.2 8.5 1.0 CA A:CYS112 4.2 17.3 1.0 CD2 A:HIS77 4.3 8.5 1.0 C A:CYS112 4.7 17.3 1.0 CB A:MET114 4.7 29.5 1.0 O A:CYS112 4.7 17.3 1.0 C A:MET114 4.9 19.4 1.0 C A:PRO111 5.0 19.4 1.0

Zinc binding site 2 out of 2 in the Identification of Function and Mechanistic Insights of Guanine Deaminase From Nitrosomonas Europaea


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Identification of Function and Mechanistic Insights of Guanine Deaminase From Nitrosomonas Europaea within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn201 b:22.0 occ:1.00 ND1 B:HIS77 2.2 7.9 1.0 SG B:CYS112 2.4 15.7 1.0 SG B:CYS115 2.4 12.9 1.0 CG B:HIS77 3.1 7.9 1.0 CE1 B:HIS77 3.2 7.9 1.0 CB B:CYS115 3.3 12.9 1.0 CB B:HIS77 3.4 7.9 1.0 CB B:CYS112 3.5 15.7 1.0 N B:CYS112 3.9 21.8 1.0 N B:CYS115 3.9 18.6 1.0 O B:HOH305 4.0 31.6 1.0 N3 B:AZG202 4.0 22.1 1.0 C4 B:AZG202 4.0 22.1 1.0 CE B:MET114 4.2 23.1 1.0 CA B:CYS115 4.2 18.6 1.0 CA B:CYS112 4.3 21.8 1.0 N9 B:AZG202 4.3 22.1 1.0 CD2 B:HIS77 4.3 7.9 1.0 NE2 B:HIS77 4.3 7.9 1.0 C2 B:AZG202 4.5 22.1 1.0 C5 B:AZG202 4.6 22.1 1.0 CB B:MET114 4.8 23.1 1.0 N8 B:AZG202 4.8 22.1 1.0 O B:CYS112 4.8 21.8 1.0 C B:CYS112 4.8 21.8 1.0 CA B:HIS77 4.9 15.4 1.0 C B:PRO111 5.0 12.1 1.0 N7 B:AZG202 5.0 22.1 1.0

A.Bitra, B.Hussain, A.S.Tanwar, R.Anand. Identification of Function and Mechanistic Insights of Guanine Deaminase From Nitrosomonas Europaea: Role of the C-Terminal Loop in Catalysis Biochemistry V. 52 3512 2013.
ISSN: ISSN 0006-2960
PubMed: 23557066
DOI: 10.1021/BI400068G