Atomistry » Zinc » PDB 4g2y-4gg9 » 4gg9
Atomistry »
  Zinc »
    PDB 4g2y-4gg9 »
      4gg9 »

Zinc in PDB 4gg9: Trna Guanine Transglycosylase in Complex with Thiophene-Substituted Lin-Benzohypoxanthine Inhibitor

Enzymatic activity of Trna Guanine Transglycosylase in Complex with Thiophene-Substituted Lin-Benzohypoxanthine Inhibitor

All present enzymatic activity of Trna Guanine Transglycosylase in Complex with Thiophene-Substituted Lin-Benzohypoxanthine Inhibitor:
2.4.2.29;

Protein crystallography data

The structure of Trna Guanine Transglycosylase in Complex with Thiophene-Substituted Lin-Benzohypoxanthine Inhibitor, PDB code: 4gg9 was solved by F.Immekus, G.Klebe, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 30.00 / 1.48
Space group C 1 2 1
Cell size a, b, c (Å), α, β, γ (°) 91.167, 64.983, 70.734, 90.00, 96.19, 90.00
R / Rfree (%) 14.1 / 18.8

Zinc Binding Sites:

The binding sites of Zinc atom in the Trna Guanine Transglycosylase in Complex with Thiophene-Substituted Lin-Benzohypoxanthine Inhibitor (pdb code 4gg9). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Trna Guanine Transglycosylase in Complex with Thiophene-Substituted Lin-Benzohypoxanthine Inhibitor, PDB code: 4gg9:

Zinc binding site 1 out of 1 in 4gg9

Go back to Zinc Binding Sites List in 4gg9
Zinc binding site 1 out of 1 in the Trna Guanine Transglycosylase in Complex with Thiophene-Substituted Lin-Benzohypoxanthine Inhibitor


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Trna Guanine Transglycosylase in Complex with Thiophene-Substituted Lin-Benzohypoxanthine Inhibitor within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn1401

b:13.1
occ:1.00
 ND1 A:HIS349 2.2 13.0 1.0
SG A:CYS318 2.3 14.9 1.0
SG A:CYS323 2.3 13.3 1.0
SG A:CYS320 2.3 12.7 1.0
CE1 A:HIS349 3.0 14.1 1.0
CB A:CYS318 3.3 14.2 1.0
CB A:CYS323 3.3 12.3 1.0
CG A:HIS349 3.3 10.4 1.0
CB A:CYS320 3.3 13.7 1.0
CB A:HIS349 3.7 10.5 1.0
N A:CYS323 3.9 11.9 1.0
N A:CYS320 4.1 14.1 1.0
CA A:HIS349 4.1 10.4 1.0
CA A:CYS320 4.2 13.6 1.0
NE2 A:HIS349 4.2 13.8 1.0
CA A:CYS323 4.2 12.9 1.0
CD2 A:HIS349 4.3 12.1 1.0
CA A:CYS318 4.6 16.4 1.0
O A:HIS349 4.6 10.9 1.0
O A:CYS320 4.6 15.0 1.0
C A:CYS320 4.6 14.1 1.0
C A:CYS318 4.7 16.1 1.0
C A:HIS349 4.8 11.1 1.0
CB A:VAL322 4.8 12.6 1.0
O A:CYS318 4.9 17.4 1.0
C A:VAL322 4.9 12.6 1.0

Reference:

F.Immekus, L.J.Barandun, F.Diederich, G.Klebe. Two-Armed Benzopurine Inhibitors of Tgt To Be Published.
Page generated: Sat Oct 26 23:17:10 2024

Last articles

Zn in 9JYW
Zn in 9IR4
Zn in 9IR3
Zn in 9GMX
Zn in 9GMW
Zn in 9JEJ
Zn in 9ERF
Zn in 9ERE
Zn in 9EGV
Zn in 9EGW
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy