Zinc in PDB 4g82: Crystal Structure of P73 Dna-Binding Domain Tetramer Bound to A Full Response-Element

The structure of Crystal Structure of P73 Dna-Binding Domain Tetramer Bound to A Full Response-Element, PDB code: 4g82 was solved by A.S.Ethayathulla, H.Viadiu, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	43.87 / 3.10
Space group	P 61
Cell size a, b, c (Å), α, β, γ (°)	175.472, 175.472, 34.317, 90.00, 90.00, 120.00
R / Rfree (%)	23.8 / 26.8

The binding sites of Zinc atom in the Crystal Structure of P73 Dna-Binding Domain Tetramer Bound to A Full Response-Element (pdb code 4g82). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of P73 Dna-Binding Domain Tetramer Bound to A Full Response-Element, PDB code: 4g82:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of P73 Dna-Binding Domain Tetramer Bound to A Full Response-Element


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of P73 Dna-Binding Domain Tetramer Bound to A Full Response-Element within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn401 b:28.0 occ:1.00 ND1 A:HIS197 2.0 21.6 1.0 SG A:CYS194 2.3 21.1 1.0 SG A:CYS258 2.4 15.8 1.0 SG A:CYS262 2.5 48.8 1.0 CE1 A:HIS197 2.9 28.4 1.0 CB A:CYS262 3.0 30.0 1.0 CB A:CYS258 3.1 13.7 1.0 CG A:HIS197 3.1 31.5 1.0 CB A:CYS194 3.2 24.1 1.0 CB A:HIS197 3.5 33.4 1.0 CA A:CYS258 3.6 5.7 1.0 N A:CYS194 4.0 34.4 1.0 NE2 A:HIS197 4.0 35.8 1.0 CD2 A:HIS197 4.2 35.7 1.0 CA A:CYS194 4.2 30.2 1.0 N A:ASN259 4.3 9.7 1.0 O A:MET257 4.3 22.6 1.0 C A:CYS258 4.4 8.6 1.0 CA A:CYS262 4.5 40.7 1.0 N A:HIS197 4.6 54.4 1.0 N A:CYS258 4.7 15.0 1.0 CA A:HIS197 4.7 43.5 1.0 O A:CYS194 4.8 41.3 1.0 C A:CYS194 4.8 37.4 1.0 O A:ASN259 4.9 17.1 1.0 C A:MET257 5.0 19.9 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of P73 Dna-Binding Domain Tetramer Bound to A Full Response-Element


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of P73 Dna-Binding Domain Tetramer Bound to A Full Response-Element within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn401 b:44.1 occ:1.00 ND1 B:HIS197 2.0 21.7 1.0 SG B:CYS258 2.3 52.8 1.0 SG B:CYS194 2.3 34.2 1.0 SG B:CYS262 2.3 27.3 1.0 CE1 B:HIS197 2.9 23.9 1.0 CG B:HIS197 3.0 26.2 1.0 CB B:CYS262 3.1 32.6 1.0 CB B:CYS194 3.2 23.6 1.0 CB B:CYS258 3.3 25.7 1.0 CB B:HIS197 3.3 26.7 1.0 N B:CYS194 3.7 43.2 1.0 CA B:CYS258 3.9 22.6 1.0 CA B:CYS194 4.0 35.5 1.0 NE2 B:HIS197 4.1 28.0 1.0 CD2 B:HIS197 4.1 29.2 1.0 CA B:CYS262 4.3 43.5 1.0 N B:HIS197 4.4 42.1 1.0 CA B:HIS197 4.5 34.7 1.0 O B:CYS194 4.5 11.0 1.0 O B:MET257 4.5 16.1 1.0 C B:CYS194 4.6 32.9 1.0 N B:VAL263 4.8 61.9 1.0 N B:ASN259 4.8 23.5 1.0 C B:CYS262 4.8 57.5 1.0 C B:ARG193 4.9 30.8 1.0 C B:CYS258 4.9 19.5 1.0 N B:CYS258 5.0 26.4 1.0

A.S.Ethayathulla, H.Viadiu. Crystal Structure of P73 Dna-Binding Domain Tetramer Bound to A Full Response-Element J.Biol.Chem. 2013.
ISSN: ESSN 1083-351X