Atomistry » Zinc » PDB 4fkd-4fvo » 4fvk
Atomistry »
  Zinc »
    PDB 4fkd-4fvo »
      4fvk »

Zinc in PDB 4fvk: Structural and Functional Characterization of Neuraminidase-Like Molecule N10 Derived From Bat Influenza A Virus

Enzymatic activity of Structural and Functional Characterization of Neuraminidase-Like Molecule N10 Derived From Bat Influenza A Virus

All present enzymatic activity of Structural and Functional Characterization of Neuraminidase-Like Molecule N10 Derived From Bat Influenza A Virus:
3.2.1.18;

Protein crystallography data

The structure of Structural and Functional Characterization of Neuraminidase-Like Molecule N10 Derived From Bat Influenza A Virus, PDB code: 4fvk was solved by Q.Li, X.M.Sun, Z.X.Li, Y.Liu, C.J.Vavricka, J.X.Qi, G.F.Gao, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 41.03 / 2.20
Space group P 4 21 2
Cell size a, b, c (Å), α, β, γ (°) 122.496, 122.496, 110.504, 90.00, 90.00, 90.00
R / Rfree (%) 20.7 / 24.6

Other elements in 4fvk:

The structure of Structural and Functional Characterization of Neuraminidase-Like Molecule N10 Derived From Bat Influenza A Virus also contains other interesting chemical elements:

Calcium (Ca) 2 atoms

Zinc Binding Sites:

The binding sites of Zinc atom in the Structural and Functional Characterization of Neuraminidase-Like Molecule N10 Derived From Bat Influenza A Virus (pdb code 4fvk). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 6 binding sites of Zinc where determined in the Structural and Functional Characterization of Neuraminidase-Like Molecule N10 Derived From Bat Influenza A Virus, PDB code: 4fvk:
Jump to Zinc binding site number: 1; 2; 3; 4; 5; 6;

Zinc binding site 1 out of 6 in 4fvk

Go back to Zinc Binding Sites List in 4fvk
Zinc binding site 1 out of 6 in the Structural and Functional Characterization of Neuraminidase-Like Molecule N10 Derived From Bat Influenza A Virus


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structural and Functional Characterization of Neuraminidase-Like Molecule N10 Derived From Bat Influenza A Virus within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn502

b:14.4
occ:1.00
 OE1 A:GLU442 2.0 23.4 1.0
O A:HOH784 2.0 30.0 1.0
O A:HOH601 2.1 40.5 1.0
O A:HOH662 2.1 40.5 1.0
OG A:SER166 2.7 20.1 1.0
CD A:GLU442 2.7 26.8 1.0
OE2 A:GLU442 2.8 27.4 1.0
CB A:SER166 3.7 21.9 1.0
O A:HOH673 3.8 40.5 1.0
CG A:GLU442 4.2 26.1 1.0
N A:SER166 4.2 19.1 1.0
O A:ILE115 4.3 20.8 1.0
NE1 A:TRP106 4.3 21.3 1.0
CD2 A:LEU114 4.5 25.2 1.0
NZ A:LYS131 4.6 21.9 1.0
CA A:SER166 4.6 21.1 1.0
CD1 A:TRP106 4.7 21.1 1.0
CG A:LEU114 4.8 25.7 1.0
OG A:SER117 4.8 20.4 1.0
O A:HOH642 4.8 40.5 1.0

Zinc binding site 2 out of 6 in 4fvk

Go back to Zinc Binding Sites List in 4fvk
Zinc binding site 2 out of 6 in the Structural and Functional Characterization of Neuraminidase-Like Molecule N10 Derived From Bat Influenza A Virus


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Structural and Functional Characterization of Neuraminidase-Like Molecule N10 Derived From Bat Influenza A Virus within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn503

b:53.3
occ:1.00
 OE1 A:GLU386 2.0 46.1 1.0
O A:HOH613 2.1 40.5 1.0
O A:HOH732 2.1 40.5 1.0
OG1 A:THR388 2.6 42.6 1.0
CD A:GLU386 3.0 49.8 1.0
CB A:THR388 3.4 38.9 1.0
CG A:GLU386 3.5 44.6 1.0
ND2 A:ASN381 4.0 37.7 1.0
OE2 A:GLU386 4.1 50.0 1.0
CG2 A:THR388 4.1 40.5 1.0
O A:HOH686 4.5 40.5 1.0
O A:HOH781 4.5 40.9 1.0
CA A:THR388 4.6 40.5 1.0
N A:THR388 4.7 36.5 1.0
O A:HOH709 4.7 40.5 1.0
CB A:GLU386 5.0 43.5 1.0

Zinc binding site 3 out of 6 in 4fvk

Go back to Zinc Binding Sites List in 4fvk
Zinc binding site 3 out of 6 in the Structural and Functional Characterization of Neuraminidase-Like Molecule N10 Derived From Bat Influenza A Virus


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Structural and Functional Characterization of Neuraminidase-Like Molecule N10 Derived From Bat Influenza A Virus within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn504

b:49.7
occ:1.00
 O A:HOH688 2.0 40.5 1.0
O A:HOH643 2.1 40.5 1.0
O A:TRP154 2.4 33.2 1.0
OE2 A:GLU156 2.7 37.3 1.0
OE1 A:GLU156 3.2 43.9 1.0
CD A:GLU156 3.3 37.7 1.0
C A:TRP154 3.4 33.0 1.0
CA A:TRP154 3.8 33.8 1.0
CB A:TRP154 4.0 35.5 1.0
NH2 A:ARG178 4.4 51.8 1.0
N A:GLU155 4.5 28.8 1.0
CG A:GLU156 4.7 30.8 1.0
O A:HOH744 4.7 40.9 1.0
CA A:GLU155 4.8 28.6 1.0

Zinc binding site 4 out of 6 in 4fvk

Go back to Zinc Binding Sites List in 4fvk
Zinc binding site 4 out of 6 in the Structural and Functional Characterization of Neuraminidase-Like Molecule N10 Derived From Bat Influenza A Virus


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Structural and Functional Characterization of Neuraminidase-Like Molecule N10 Derived From Bat Influenza A Virus within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Zn502

b:25.3
occ:1.00
 O B:HOH605 2.0 40.5 1.0
O B:HOH663 2.0 40.9 1.0
OE1 B:GLU442 2.1 37.4 1.0
O B:HOH601 2.1 40.5 1.0
OG B:SER166 2.7 32.5 1.0
OE2 B:GLU442 2.7 39.6 1.0
CD B:GLU442 2.7 40.4 1.0
O B:HOH616 3.7 40.5 1.0
CB B:SER166 3.8 33.3 1.0
O B:HOH680 3.9 40.9 1.0
CG B:GLU442 4.2 40.4 1.0
N B:SER166 4.3 32.4 1.0
O B:ILE115 4.4 32.6 1.0
NE1 B:TRP106 4.5 41.7 1.0
OG B:SER117 4.6 33.8 1.0
CA B:SER166 4.7 32.9 1.0
NZ B:LYS131 4.7 37.8 1.0
CD1 B:LEU114 4.7 37.4 1.0
CD2 B:LEU114 4.7 36.3 1.0
CG B:LEU114 4.8 33.6 1.0
CD1 B:TRP106 4.9 41.5 1.0

Zinc binding site 5 out of 6 in 4fvk

Go back to Zinc Binding Sites List in 4fvk
Zinc binding site 5 out of 6 in the Structural and Functional Characterization of Neuraminidase-Like Molecule N10 Derived From Bat Influenza A Virus


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 5 of Structural and Functional Characterization of Neuraminidase-Like Molecule N10 Derived From Bat Influenza A Virus within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Zn503

b:86.2
occ:1.00
 OE1 B:GLU386 2.0 96.8 1.0
O B:HOH696 2.1 30.0 1.0
O B:HOH635 2.1 40.5 1.0
OG1 B:THR388 2.6 92.8 1.0
CD B:GLU386 2.9 96.9 1.0
CG B:GLU386 3.3 92.3 1.0
CB B:THR388 3.4 87.4 1.0
OE2 B:GLU386 3.9 100.0 1.0
O B:HOH692 4.2 40.9 1.0
ND2 B:ASN381 4.2 79.4 1.0
CG2 B:THR388 4.3 85.5 1.0
CA B:THR388 4.7 85.7 1.0
N B:THR388 4.7 84.2 1.0
CB B:GLU386 4.8 91.4 1.0

Zinc binding site 6 out of 6 in 4fvk

Go back to Zinc Binding Sites List in 4fvk
Zinc binding site 6 out of 6 in the Structural and Functional Characterization of Neuraminidase-Like Molecule N10 Derived From Bat Influenza A Virus


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 6 of Structural and Functional Characterization of Neuraminidase-Like Molecule N10 Derived From Bat Influenza A Virus within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Zn504

b:61.1
occ:1.00
 O B:HOH660 2.1 40.5 1.0
O B:TRP154 2.4 53.1 1.0
OE2 B:GLU156 2.8 61.0 1.0
OE1 B:GLU156 3.0 65.9 1.0
CD B:GLU156 3.3 61.8 1.0
C B:TRP154 3.5 53.4 1.0
CA B:TRP154 4.0 54.7 1.0
CB B:TRP154 4.2 54.7 1.0
N B:GLU155 4.6 49.7 1.0
CG B:GLU156 4.7 55.1 1.0
NH2 B:ARG178 4.8 68.6 1.0
CA B:GLU155 4.9 50.0 1.0
N B:GLU156 5.0 53.5 1.0

Reference:

Q.Li, X.M.Sun, Z.X.Li, Y.Liu, C.J.Vavricka, J.X.Qi, G.F.Gao. Structural and Functional Characterization of Neuraminidase-Like Molecule N10 Derived From Bat Influenza A Virus Proc.Natl.Acad.Sci.Usa V. 109 18897 2012.
ISSN: ISSN 0027-8424
PubMed: 23012237
DOI: 10.1073/PNAS.1211037109
Page generated: Sat Oct 26 22:56:44 2024

Last articles

Zn in 9JPJ
Zn in 9JP7
Zn in 9JPK
Zn in 9JPL
Zn in 9GN6
Zn in 9GN7
Zn in 9GKU
Zn in 9GKW
Zn in 9GKX
Zn in 9GL0
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy