Atomistry » Zinc » PDB 4fkd-4fvo » 4fmn
Atomistry »
  Zinc »
    PDB 4fkd-4fvo »
      4fmn »

Zinc in PDB 4fmn: Structure of the C-Terminal Domain of the Saccharomyces Cerevisiae Mutl Alpha (MLH1/PMS1) Heterodimer Bound to A Fragment of NTG2

Protein crystallography data

The structure of Structure of the C-Terminal Domain of the Saccharomyces Cerevisiae Mutl Alpha (MLH1/PMS1) Heterodimer Bound to A Fragment of NTG2, PDB code: 4fmn was solved by E.Gueneau, P.Legrand, J.B.Charbonnier, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 31.63 / 2.69
Space group C 1 2 1
Cell size a, b, c (Å), α, β, γ (°) 190.940, 66.300, 74.110, 90.00, 90.15, 90.00
R / Rfree (%) 16.9 / 19.2

Zinc Binding Sites:

The binding sites of Zinc atom in the Structure of the C-Terminal Domain of the Saccharomyces Cerevisiae Mutl Alpha (MLH1/PMS1) Heterodimer Bound to A Fragment of NTG2 (pdb code 4fmn). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Structure of the C-Terminal Domain of the Saccharomyces Cerevisiae Mutl Alpha (MLH1/PMS1) Heterodimer Bound to A Fragment of NTG2, PDB code: 4fmn:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in 4fmn

Go back to Zinc Binding Sites List in 4fmn
Zinc binding site 1 out of 2 in the Structure of the C-Terminal Domain of the Saccharomyces Cerevisiae Mutl Alpha (MLH1/PMS1) Heterodimer Bound to A Fragment of NTG2


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of the C-Terminal Domain of the Saccharomyces Cerevisiae Mutl Alpha (MLH1/PMS1) Heterodimer Bound to A Fragment of NTG2 within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Zn901

b:61.4
occ:1.00
OE1 B:GLU707 1.9 61.2 1.0
NE2 B:HIS703 2.0 55.6 1.0
SG A:CYS769 2.3 77.8 1.0
SG B:CYS817 2.4 60.9 1.0
CD B:GLU707 3.0 59.2 1.0
CE1 B:HIS703 3.0 54.7 1.0
CB A:CYS769 3.1 75.7 1.0
CD2 B:HIS703 3.1 55.2 1.0
CB B:CYS817 3.2 56.8 1.0
ZN B:ZN902 3.4 61.4 1.0
OE2 B:GLU707 3.5 49.6 1.0
CA B:CYS817 3.7 55.8 1.0
O A:HOH941 4.0 50.0 1.0
CE1 B:HIS850 4.1 60.9 1.0
ND1 B:HIS703 4.2 54.8 1.0
CG B:HIS703 4.2 52.6 1.0
ND1 B:HIS850 4.2 61.7 1.0
CG B:GLU707 4.2 47.0 1.0
O B:CYS817 4.4 63.0 1.0
CA A:CYS769 4.5 75.2 1.0
C B:CYS817 4.5 62.0 1.0
CB B:GLU707 4.7 49.3 1.0
N B:CYS817 4.8 55.9 1.0
N A:CYS769 4.8 71.8 1.0

Zinc binding site 2 out of 2 in 4fmn

Go back to Zinc Binding Sites List in 4fmn
Zinc binding site 2 out of 2 in the Structure of the C-Terminal Domain of the Saccharomyces Cerevisiae Mutl Alpha (MLH1/PMS1) Heterodimer Bound to A Fragment of NTG2


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Structure of the C-Terminal Domain of the Saccharomyces Cerevisiae Mutl Alpha (MLH1/PMS1) Heterodimer Bound to A Fragment of NTG2 within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Zn902

b:61.4
occ:1.00
ND1 B:HIS850 1.9 61.7 1.0
OE2 B:GLU707 1.9 49.6 1.0
SG A:CYS769 2.3 77.8 1.0
SG B:CYS848 2.3 61.3 1.0
CE1 B:HIS850 2.8 60.9 1.0
CD B:GLU707 2.9 59.2 1.0
CG B:HIS850 3.0 61.5 1.0
CB A:CYS769 3.1 75.7 1.0
OE1 B:GLU707 3.2 61.2 1.0
CB B:CYS848 3.4 56.3 1.0
ZN B:ZN901 3.4 61.4 1.0
CB B:HIS850 3.5 59.9 1.0
N B:HIS850 3.8 61.8 1.0
CA A:CYS769 4.0 75.2 1.0
NE2 B:HIS850 4.0 62.2 1.0
CD2 B:HIS850 4.1 63.4 1.0
CG B:GLU707 4.2 47.0 1.0
CA B:HIS850 4.3 61.4 1.0
CD B:PRO849 4.3 61.4 1.0
N B:PRO849 4.4 61.7 1.0
CG B:PRO849 4.5 66.2 1.0
CA B:CYS848 4.6 58.6 1.0
C B:CYS848 4.6 65.0 1.0
CG B:ARG852 4.7 61.7 1.0
NE2 B:HIS703 4.8 55.6 1.0
N A:CYS769 4.9 71.8 1.0
C B:PRO849 4.9 69.0 1.0
CB B:GLU707 5.0 49.3 1.0

Reference:

E.Gueneau, C.Dherin, P.Legrand, C.Tellier-Lebegue, B.Gilquin, P.Bonnesoeur, F.Londino, C.Quemener, M.H.Le Du, J.A.Marquez, M.Moutiez, M.Gondry, S.Boiteux, J.B.Charbonnier. Structure of the Mutl Alpha C-Terminal Domain Reveals How MLH1 Contributes to PMS1 Endonuclease Site. Nat.Struct.Mol.Biol. V. 20 461 2013.
ISSN: ISSN 1545-9993
PubMed: 23435383
DOI: 10.1038/NSMB.2511
Page generated: Sat Oct 26 22:49:37 2024

Last articles

Zn in 9JYW
Zn in 9IR4
Zn in 9IR3
Zn in 9GMX
Zn in 9GMW
Zn in 9JEJ
Zn in 9ERF
Zn in 9ERE
Zn in 9EGV
Zn in 9EGW
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy