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Atomistry » Zinc » PDB 4f6n-4fkb » 4f9a | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Zinc » PDB 4f6n-4fkb » 4f9a » |
Zinc in PDB 4f9a: Crystal Structure of Human Phosphodiesterase 4B with Regulatory Domain and D155988Enzymatic activity of Crystal Structure of Human Phosphodiesterase 4B with Regulatory Domain and D155988
All present enzymatic activity of Crystal Structure of Human Phosphodiesterase 4B with Regulatory Domain and D155988:
3.1.4.17; Protein crystallography data
The structure of Crystal Structure of Human Phosphodiesterase 4B with Regulatory Domain and D155988, PDB code: 4f9a
was solved by
B.L.Staker,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4f9a:
The structure of Crystal Structure of Human Phosphodiesterase 4B with Regulatory Domain and D155988 also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Crystal Structure of Human Phosphodiesterase 4B with Regulatory Domain and D155988
(pdb code 4f9a). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Human Phosphodiesterase 4B with Regulatory Domain and D155988, PDB code: 4f9a: Jump to Zinc binding site number: 1; 2; Zinc binding site 1 out of 2 in 4f9aGo back to Zinc Binding Sites List in 4f9a
Zinc binding site 1 out
of 2 in the Crystal Structure of Human Phosphodiesterase 4B with Regulatory Domain and D155988
Mono view Stereo pair view
Zinc binding site 2 out of 2 in 4f9aGo back to Zinc Binding Sites List in 4f9a
Zinc binding site 2 out
of 2 in the Crystal Structure of Human Phosphodiesterase 4B with Regulatory Domain and D155988
Mono view Stereo pair view
Reference:
A.B.Burgin,
O.T.Magnusson,
J.Singh,
P.Witte,
B.L.Staker,
J.M.Bjornsson,
M.Thorsteinsdottir,
S.Hrafnsdottir,
T.Hagen,
A.S.Kiselyov,
L.J.Stewart,
M.E.Gurney.
Design of Phosphodiesterase 4D (PDE4D) Allosteric Modulators For Enhancing Cognition with Improved Safety. Nat.Biotechnol. V. 28 63 2010.
Page generated: Wed Dec 16 05:17:09 2020
ISSN: ISSN 1087-0156 PubMed: 20037581 DOI: 10.1038/NBT.1598 |
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