Zinc in PDB 4f2j: Crystal Structure of ZNF217 Bound to Dna, P6522 Crystal Form

The structure of Crystal Structure of ZNF217 Bound to Dna, P6522 Crystal Form, PDB code: 4f2j was solved by M.S.Vandevenne, D.A.Jacques, J.M.Guss, J.P.Mackay, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	48.31 / 2.64
Space group	P 65 2 2
Cell size a, b, c (Å), α, β, γ (°)	56.928, 56.928, 242.542, 90.00, 90.00, 120.00
R / Rfree (%)	25.2 / 26.4

The binding sites of Zinc atom in the Crystal Structure of ZNF217 Bound to Dna, P6522 Crystal Form (pdb code 4f2j). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of ZNF217 Bound to Dna, P6522 Crystal Form, PDB code: 4f2j:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of ZNF217 Bound to Dna, P6522 Crystal Form


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of ZNF217 Bound to Dna, P6522 Crystal Form within 5.0Å range: probe atom residue distance (Å) B Occ C:Zn601 b:0.1 occ:1.00 SG C:CYS504 2.0 0.9 1.0 SG C:CYS501 2.1 0.8 1.0 NE2 C:HIS517 2.1 94.2 1.0 NE2 C:HIS522 2.3 0.9 1.0 CE1 C:HIS517 2.9 0.1 1.0 CE1 C:HIS522 3.3 0.6 1.0 CD2 C:HIS517 3.3 99.5 1.0 N C:CYS504 3.3 0.4 1.0 CD2 C:HIS522 3.3 0.7 1.0 CB C:CYS501 3.3 0.3 1.0 CB C:CYS504 3.4 0.8 1.0 CA C:CYS504 3.8 0.6 1.0 CB C:PHE503 3.9 0.8 1.0 ND1 C:HIS517 4.1 89.8 1.0 C C:PHE503 4.2 0.9 1.0 O C:CYS504 4.2 0.7 1.0 CG C:HIS517 4.3 89.4 1.0 C C:CYS504 4.3 0.0 1.0 ND1 C:HIS522 4.3 0.7 1.0 CG C:HIS522 4.4 0.6 1.0 CA C:PHE503 4.4 0.1 1.0 N C:PHE503 4.5 1.0 1.0 CB C:TYR506 4.6 0.1 1.0 CA C:CYS501 4.7 0.6 1.0 CD2 C:TYR506 5.0 98.7 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of ZNF217 Bound to Dna, P6522 Crystal Form


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of ZNF217 Bound to Dna, P6522 Crystal Form within 5.0Å range: probe atom residue distance (Å) B Occ C:Zn602 b:87.0 occ:1.00 NE2 C:HIS493 2.0 71.5 1.0 NE2 C:HIS489 2.0 62.6 1.0 SG C:CYS473 2.0 83.6 1.0 SG C:CYS476 2.3 82.5 1.0 CE1 C:HIS489 2.8 75.0 1.0 CE1 C:HIS493 2.8 80.1 1.0 CB C:CYS473 2.9 85.4 1.0 CD2 C:HIS493 3.1 74.5 1.0 CD2 C:HIS489 3.1 64.8 1.0 CB C:CYS476 3.2 93.2 1.0 N C:CYS476 3.7 95.3 1.0 ND1 C:HIS489 4.0 61.0 1.0 ND1 C:HIS493 4.0 68.0 1.0 CA C:CYS476 4.1 97.6 1.0 CG C:HIS489 4.2 56.3 1.0 CG C:HIS493 4.2 81.7 1.0 CA C:CYS473 4.4 86.0 1.0 CZ C:PHE480 4.5 84.3 1.0 CB C:TYR475 4.6 93.8 1.0 CE2 C:PHE480 4.6 88.8 1.0 C C:TYR475 4.8 99.1 1.0 C C:CYS476 4.8 1.0 1.0 C C:CYS473 4.9 91.5 1.0 N C:TYR475 4.9 90.7 1.0 N C:GLY477 4.9 0.9 1.0

M.S.Vandevenne, D.A.Jacques, C.Artuz, C.D.Nguyen, A.H.Kwan, D.J.Segal, J.M.Matthews, M.Crossley, J.M.Guss, J.P.Mackay. New Insights Into Dna Recognition By Zinc Fingers Revealed By Structural Analysis of the Oncoprotein ZNF217 J.Biol.Chem. V. 288 10616 2013.
ISSN: ISSN 0021-9258
PubMed: 23436653
DOI: 10.1074/JBC.M112.441451