Zinc in PDB 4f14: Structure of the SH3 Domain of Human Nebulette in Complex with A Peptide of XIRP2

The structure of Structure of the SH3 Domain of Human Nebulette in Complex with A Peptide of XIRP2, PDB code: 4f14 was solved by F.Sauer, J.Vahokoski, M.Wilmanns, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	18.49 / 1.20
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	35.640, 38.420, 43.260, 90.00, 90.00, 90.00
R / Rfree (%)	14.4 / 17.1

The binding sites of Zinc atom in the Structure of the SH3 Domain of Human Nebulette in Complex with A Peptide of XIRP2 (pdb code 4f14). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Structure of the SH3 Domain of Human Nebulette in Complex with A Peptide of XIRP2, PDB code: 4f14:

Zinc binding site 1 out of 1 in the Structure of the SH3 Domain of Human Nebulette in Complex with A Peptide of XIRP2


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of the SH3 Domain of Human Nebulette in Complex with A Peptide of XIRP2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1101 b:15.6 occ:1.00 OE1 A:GLU970 2.0 23.3 1.0 OD1 A:ASP969 2.1 18.6 1.0 O A:HOH1244 2.2 32.8 1.0 CD A:GLU970 2.8 25.4 1.0 OE2 A:GLU970 3.0 27.2 1.0 CG A:ASP969 3.1 20.5 1.0 O A:HOH1287 3.2 49.9 1.0 H A:GLU970 3.4 20.5 1.0 OD2 A:ASP969 3.6 23.8 1.0 HA A:ASP969 4.0 18.9 1.0 CG A:GLU970 4.2 23.8 1.0 HB2 A:GLU970 4.3 24.8 1.0 N A:GLU970 4.3 17.1 1.0 O A:HOH1267 4.3 59.4 1.0 CB A:ASP969 4.4 17.2 1.0 HG2 A:GLU970 4.6 28.5 1.0 CA A:ASP969 4.6 15.7 1.0 O A:HOH1231 4.6 36.0 1.0 CB A:GLU970 4.7 20.6 1.0 HG3 A:GLU970 4.8 28.5 1.0 HB2 A:ASP969 4.9 20.6 1.0 O A:HOH1280 4.9 47.3 1.0

S.Eulitz, F.Sauer, M.C.Pelissier, P.Boisguerin, S.Molt, J.Schuld, Z.Orfanos, R.A.Kley, R.Volkmer, M.Wilmanns, G.Kirfel, P.F.Van Der Ven, D.O.Furst. Identification of Xin-Repeat Proteins As Novel Ligands of the SH3 Domains of Nebulin and Nebulette and Analysis of Their Interaction During Myofibril Formation and Remodeling. Mol Biol Cell V. 24 3215 2013.
ISSN: ISSN 1059-1524
PubMed: 23985323
DOI: 10.1091/MBC.E13-04-0202