Atomistry » Zinc » PDB 4dyu-4ebb » 4e7v
Atomistry »
  Zinc »
    PDB 4dyu-4ebb »
      4e7v »

Zinc in PDB 4e7v: The Structure of R6 Bovine Insulin

Protein crystallography data

The structure of The Structure of R6 Bovine Insulin, PDB code: 4e7v was solved by P.Harris, C.G.Frankaer, M.V.Knudsen, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 28.88 / 1.80
Space group H 3 1
Cell size a, b, c (Å), α, β, γ (°) 156.240, 156.240, 78.880, 90.00, 90.00, 120.00
R / Rfree (%) 20.9 / 27.2

Other elements in 4e7v:

The structure of The Structure of R6 Bovine Insulin also contains other interesting chemical elements:

Chlorine (Cl) 8 atoms

Zinc Binding Sites:

The binding sites of Zinc atom in the The Structure of R6 Bovine Insulin (pdb code 4e7v). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 8 binding sites of Zinc where determined in the The Structure of R6 Bovine Insulin, PDB code: 4e7v:
Jump to Zinc binding site number: 1; 2; 3; 4; 5; 6; 7; 8;

Zinc binding site 1 out of 8 in 4e7v

Go back to Zinc Binding Sites List in 4e7v
Zinc binding site 1 out of 8 in the The Structure of R6 Bovine Insulin


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of The Structure of R6 Bovine Insulin within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Zn101

b:24.2
occ:1.00
NE2 J:HIS10 2.0 22.8 1.0
NE2 F:HIS10 2.1 19.2 1.0
NE2 B:HIS10 2.1 23.3 1.0
CL F:CL101 2.2 25.9 1.0
CD2 F:HIS10 3.0 21.9 1.0
CD2 B:HIS10 3.0 18.1 1.0
CE1 J:HIS10 3.0 33.3 1.0
CD2 J:HIS10 3.0 18.1 1.0
CE1 F:HIS10 3.1 25.1 1.0
CE1 B:HIS10 3.1 32.5 1.0
ND1 J:HIS10 4.1 27.3 1.0
CG F:HIS10 4.1 25.2 1.0
ND1 F:HIS10 4.2 30.9 1.0
CG B:HIS10 4.2 20.8 1.0
CG J:HIS10 4.2 17.5 1.0
ND1 B:HIS10 4.2 28.4 1.0
O B:LEU6 4.8 24.8 1.0
CB J:LEU6 4.8 24.5 1.0
O J:LEU6 4.8 29.7 1.0
CB B:LEU6 4.8 27.8 1.0
O B:HOH217 4.9 46.1 1.0
O F:LEU6 4.9 27.9 1.0
CB F:LEU6 5.0 28.8 1.0

Zinc binding site 2 out of 8 in 4e7v

Go back to Zinc Binding Sites List in 4e7v
Zinc binding site 2 out of 8 in the The Structure of R6 Bovine Insulin


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of The Structure of R6 Bovine Insulin within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Zn101

b:21.1
occ:1.00
NE2 L:HIS10 2.0 20.1 1.0
NE2 D:HIS10 2.1 19.7 1.0
NE2 H:HIS10 2.1 20.3 1.0
CL D:CL102 2.2 20.4 1.0
CD2 L:HIS10 2.9 18.4 1.0
CD2 D:HIS10 3.0 19.6 1.0
CD2 H:HIS10 3.0 21.2 1.0
CE1 L:HIS10 3.0 23.6 1.0
CE1 D:HIS10 3.1 21.7 1.0
CE1 H:HIS10 3.1 20.5 1.0
O H:HOH116 3.7 47.4 1.0
ND1 L:HIS10 4.1 25.6 1.0
CG L:HIS10 4.1 19.8 1.0
CG D:HIS10 4.2 20.9 1.0
ND1 D:HIS10 4.2 23.2 1.0
CG H:HIS10 4.2 16.8 1.0
ND1 H:HIS10 4.2 21.6 1.0
O H:HOH120 4.9 46.9 1.0
O H:HOH118 4.9 44.1 1.0
O L:LEU6 4.9 23.5 1.0
CB L:LEU6 4.9 18.7 1.0
O D:LEU6 4.9 22.6 1.0
O H:LEU6 4.9 21.8 1.0
CB H:LEU6 5.0 20.9 1.0

Zinc binding site 3 out of 8 in 4e7v

Go back to Zinc Binding Sites List in 4e7v
Zinc binding site 3 out of 8 in the The Structure of R6 Bovine Insulin


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of The Structure of R6 Bovine Insulin within 5.0Å range:
probe atom residue distance (Å) B Occ
N:Zn101

b:18.9
occ:1.00
NE2 R:HIS10 2.0 15.4 1.0
NE2 N:HIS10 2.1 16.8 1.0
NE2 V:HIS10 2.1 17.1 1.0
CL N:CL102 2.1 21.1 1.0
CE1 R:HIS10 3.0 28.7 1.0
CE1 N:HIS10 3.0 32.3 1.0
CD2 R:HIS10 3.0 15.4 1.0
CD2 V:HIS10 3.0 17.1 1.0
CE1 V:HIS10 3.1 29.5 1.0
CD2 N:HIS10 3.1 17.7 1.0
O V:HOH107 3.7 40.0 1.0
ND1 R:HIS10 4.1 22.3 1.0
ND1 N:HIS10 4.1 20.3 1.0
CG R:HIS10 4.2 18.4 1.0
ND1 V:HIS10 4.2 23.2 1.0
CG V:HIS10 4.2 15.9 1.0
CG N:HIS10 4.2 16.8 1.0
O V:HOH122 4.7 50.4 1.0
O R:LEU6 4.8 17.9 1.0
O V:LEU6 4.8 18.1 1.0
O N:LEU6 4.9 16.3 1.0
O N:HOH205 4.9 41.0 1.0
O R:HOH115 4.9 53.7 1.0
CB N:LEU6 4.9 22.7 1.0
CB R:LEU6 4.9 22.5 1.0
CB V:LEU6 5.0 21.3 1.0

Zinc binding site 4 out of 8 in 4e7v

Go back to Zinc Binding Sites List in 4e7v
Zinc binding site 4 out of 8 in the The Structure of R6 Bovine Insulin


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of The Structure of R6 Bovine Insulin within 5.0Å range:
probe atom residue distance (Å) B Occ
P:Zn101

b:21.7
occ:1.00
NE2 T:HIS10 2.1 23.2 1.0
NE2 X:HIS10 2.1 22.6 1.0
NE2 P:HIS10 2.2 21.7 1.0
CL P:CL102 2.3 23.3 1.0
CD2 T:HIS10 3.0 16.6 1.0
CD2 P:HIS10 3.0 23.3 1.0
CD2 X:HIS10 3.1 21.6 1.0
CE1 T:HIS10 3.1 21.8 1.0
CE1 X:HIS10 3.2 26.0 1.0
CE1 P:HIS10 3.2 27.8 1.0
CG T:HIS10 4.2 19.3 1.0
ND1 T:HIS10 4.2 19.9 1.0
CG P:HIS10 4.2 21.5 1.0
CG X:HIS10 4.2 19.8 1.0
ND1 X:HIS10 4.2 25.3 1.0
ND1 P:HIS10 4.3 24.5 1.0
O P:HOH203 4.7 38.8 1.0
O T:HOH108 4.8 39.4 1.0
O P:LEU6 4.8 19.0 1.0
O X:HOH105 4.9 42.0 1.0
O T:LEU6 4.9 17.0 1.0
CB T:LEU6 4.9 23.2 1.0
O X:LEU6 4.9 21.9 1.0
CB X:LEU6 4.9 22.7 1.0

Zinc binding site 5 out of 8 in 4e7v

Go back to Zinc Binding Sites List in 4e7v
Zinc binding site 5 out of 8 in the The Structure of R6 Bovine Insulin


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 5 of The Structure of R6 Bovine Insulin within 5.0Å range:
probe atom residue distance (Å) B Occ
Z:Zn101

b:20.0
occ:0.33
NE2 Z:HIS10 2.1 19.6 1.0
CL Z:CL102 2.1 24.6 0.3
CE1 Z:HIS10 3.0 31.3 1.0
CD2 Z:HIS10 3.1 19.5 1.0
O Z:HOH212 3.5 44.2 0.3
ND1 Z:HIS10 4.1 25.8 1.0
CG Z:HIS10 4.2 19.8 1.0
O Z:LEU6 4.9 19.1 1.0
CB Z:LEU6 4.9 20.9 1.0
O Z:HOH220 5.0 51.8 1.0

Zinc binding site 6 out of 8 in 4e7v

Go back to Zinc Binding Sites List in 4e7v
Zinc binding site 6 out of 8 in the The Structure of R6 Bovine Insulin


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 6 of The Structure of R6 Bovine Insulin within 5.0Å range:
probe atom residue distance (Å) B Occ
2:Zn101

b:28.5
occ:0.33
NE2 2:HIS10 2.2 27.4 1.0
CL 2:CL102 2.4 29.6 0.3
CD2 2:HIS10 3.1 26.9 1.0
CE1 2:HIS10 3.2 27.7 1.0
ND1 2:HIS10 4.3 26.7 1.0
CG 2:HIS10 4.3 25.0 1.0
O 2:HOH207 4.8 46.6 1.0
O 2:LEU6 4.9 28.3 1.0

Zinc binding site 7 out of 8 in 4e7v

Go back to Zinc Binding Sites List in 4e7v
Zinc binding site 7 out of 8 in the The Structure of R6 Bovine Insulin


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 7 of The Structure of R6 Bovine Insulin within 5.0Å range:
probe atom residue distance (Å) B Occ
4:Zn101

b:33.8
occ:0.33
NE2 4:HIS10 2.1 30.8 1.0
CL 4:CL102 2.4 34.1 0.3
CE1 4:HIS10 3.0 38.3 1.0
CD2 4:HIS10 3.1 31.2 1.0
ND1 4:HIS10 4.2 35.9 1.0
CG 4:HIS10 4.2 25.9 1.0
O 4:LEU6 4.6 38.3 1.0
CB 4:LEU6 4.8 40.1 1.0

Zinc binding site 8 out of 8 in 4e7v

Go back to Zinc Binding Sites List in 4e7v
Zinc binding site 8 out of 8 in the The Structure of R6 Bovine Insulin


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 8 of The Structure of R6 Bovine Insulin within 5.0Å range:
probe atom residue distance (Å) B Occ
6:Zn101

b:21.3
occ:0.33
NE2 6:HIS10 2.1 23.4 1.0
CL 6:CL102 2.2 23.6 0.3
CD2 6:HIS10 3.0 23.0 1.0
CE1 6:HIS10 3.1 25.7 1.0
ND1 6:HIS10 4.2 24.3 1.0
CG 6:HIS10 4.2 19.3 1.0
O 6:LEU6 4.9 25.6 1.0
CB 6:LEU6 5.0 22.1 1.0

Reference:

C.G.Frankar, M.V.Knudsen, K.Noren, E.Nazarenko, K.Stahl, P.Harris. The Structures of T(6), T(3)R(3) and R(6) Bovine Insulin: Combining X-Ray Diffraction and Absorption Spectroscopy. Acta Crystallogr.,Sect.D V. 68 1259 2012.
ISSN: ISSN 0907-4449
PubMed: 22993080
DOI: 10.1107/S090744491202625X
Page generated: Wed Dec 16 05:15:48 2020

Last articles

Zn in 7VD8
Zn in 7V1R
Zn in 7V1Q
Zn in 7VPF
Zn in 7T85
Zn in 7T5F
Zn in 7NF9
Zn in 7M4M
Zn in 7M4O
Zn in 7M4N
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy