Zinc in PDB 4e7h: Pfv Intasome Prior to 3'-Processing, Apo Form (Ui-Apo)

All present enzymatic activity of Pfv Intasome Prior to 3'-Processing, Apo Form (Ui-Apo):
2.7.7.49; 2.7.7.7; 3.1.26.4;

The structure of Pfv Intasome Prior to 3'-Processing, Apo Form (Ui-Apo), PDB code: 4e7h was solved by S.Hare, P.Cherepanov, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	36.92 / 2.57
Space group	P 41 21 2
Cell size a, b, c (Å), α, β, γ (°)	159.470, 159.470, 123.750, 90.00, 90.00, 90.00
R / Rfree (%)	18.6 / 21.9

The binding sites of Zinc atom in the Pfv Intasome Prior to 3'-Processing, Apo Form (Ui-Apo) (pdb code 4e7h). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Pfv Intasome Prior to 3'-Processing, Apo Form (Ui-Apo), PDB code: 4e7h:

Zinc binding site 1 out of 1 in the Pfv Intasome Prior to 3'-Processing, Apo Form (Ui-Apo)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Pfv Intasome Prior to 3'-Processing, Apo Form (Ui-Apo) within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn410 b:51.9 occ:1.00 NE2 A:HIS62 2.0 47.7 1.0 ND1 A:HIS66 2.0 41.5 1.0 SG A:CYS99 2.3 48.5 1.0 SG A:CYS96 2.3 56.6 1.0 CE1 A:HIS62 2.8 45.9 1.0 CE1 A:HIS66 3.0 46.5 1.0 CG A:HIS66 3.1 50.1 1.0 CD2 A:HIS62 3.1 50.3 1.0 CB A:CYS96 3.3 45.3 1.0 CB A:HIS66 3.4 33.9 1.0 CB A:CYS99 3.5 42.5 1.0 CA A:HIS66 3.9 46.5 1.0 N A:CYS99 3.9 37.7 1.0 ND1 A:HIS62 4.0 48.5 1.0 NE2 A:HIS66 4.1 52.0 1.0 CG A:HIS62 4.1 50.7 1.0 CA A:CYS99 4.2 48.7 1.0 O A:HOH543 4.2 55.9 1.0 CD2 A:HIS66 4.2 41.7 1.0 C A:HIS66 4.4 45.8 1.0 O A:HIS66 4.4 45.2 1.0 CA A:CYS96 4.7 51.2 1.0 OD1 A:ASN63 4.7 57.0 1.0 C A:GLN98 4.9 55.6 1.0 CB A:GLN98 5.0 47.7 1.0

S.Hare, G.N.Maertens, P.Cherepanov. 3'-Processing and Strand Transfer Catalysed By Retroviral Integrase in Crystallo. Embo J. V. 31 3020 2012.
ISSN: ISSN 0261-4189
PubMed: 22580823
DOI: 10.1038/EMBOJ.2012.118