Atomistry » Zinc » PDB 4d91-4dr2 » 4def
Atomistry »
  Zinc »
    PDB 4d91-4dr2 »
      4def »

Zinc in PDB 4def: Active Site Loop Dynamics of A Class Iia Fructose 1,6-Bisphosphate Aldolase From M. Tuberculosis

Enzymatic activity of Active Site Loop Dynamics of A Class Iia Fructose 1,6-Bisphosphate Aldolase From M. Tuberculosis

All present enzymatic activity of Active Site Loop Dynamics of A Class Iia Fructose 1,6-Bisphosphate Aldolase From M. Tuberculosis:
4.1.2.13;

Protein crystallography data

The structure of Active Site Loop Dynamics of A Class Iia Fructose 1,6-Bisphosphate Aldolase From M. Tuberculosis, PDB code: 4def was solved by G.C.Capodagli, S.D.Pegan, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 33.34 / 1.64
Space group I 2 2 2
Cell size a, b, c (Å), α, β, γ (°) 60.655, 119.708, 164.826, 90.00, 90.00, 90.00
R / Rfree (%) 18.9 / 19.9

Other elements in 4def:

The structure of Active Site Loop Dynamics of A Class Iia Fructose 1,6-Bisphosphate Aldolase From M. Tuberculosis also contains other interesting chemical elements:

Sodium (Na) 1 atom

Zinc Binding Sites:

The binding sites of Zinc atom in the Active Site Loop Dynamics of A Class Iia Fructose 1,6-Bisphosphate Aldolase From M. Tuberculosis (pdb code 4def). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Active Site Loop Dynamics of A Class Iia Fructose 1,6-Bisphosphate Aldolase From M. Tuberculosis, PDB code: 4def:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in 4def

Go back to Zinc Binding Sites List in 4def
Zinc binding site 1 out of 2 in the Active Site Loop Dynamics of A Class Iia Fructose 1,6-Bisphosphate Aldolase From M. Tuberculosis


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Active Site Loop Dynamics of A Class Iia Fructose 1,6-Bisphosphate Aldolase From M. Tuberculosis within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn401

b:32.9
occ:1.00
NE2 A:HIS96 2.0 28.9 1.0
O A:HOH907 2.0 37.5 1.0
ND1 A:HIS252 2.1 26.1 1.0
O A:HOH917 2.2 35.8 1.0
NE2 A:HIS212 2.2 56.2 1.0
CE1 A:HIS212 2.8 58.3 1.0
CD2 A:HIS96 3.0 27.3 1.0
CE1 A:HIS96 3.0 27.4 1.0
CE1 A:HIS252 3.0 26.7 1.0
CG A:HIS252 3.2 27.0 1.0
CD2 A:HIS212 3.4 57.5 1.0
CB A:HIS252 3.6 27.6 1.0
O A:HOH808 3.7 17.2 1.0
OD1 A:ASN274 4.0 26.0 1.0
ND1 A:HIS212 4.0 59.2 1.0
ND1 A:HIS96 4.1 27.0 1.0
CG A:HIS96 4.1 27.5 1.0
OD1 A:ASP95 4.2 27.5 1.0
NE2 A:HIS252 4.2 25.1 1.0
CD2 A:HIS252 4.3 26.0 1.0
CG A:HIS212 4.4 59.6 1.0
O A:HOH923 4.4 42.8 1.0
OD2 A:ASP95 4.5 27.6 1.0
CA A:HIS252 4.5 28.2 1.0
O A:HOH918 4.8 44.5 1.0
CG A:ASP95 4.8 27.4 1.0
N A:GLY253 4.9 35.2 1.0
CG A:ASN274 4.9 23.2 1.0
O A:HOH751 5.0 51.7 1.0
CB A:ASN274 5.0 22.7 1.0

Zinc binding site 2 out of 2 in 4def

Go back to Zinc Binding Sites List in 4def
Zinc binding site 2 out of 2 in the Active Site Loop Dynamics of A Class Iia Fructose 1,6-Bisphosphate Aldolase From M. Tuberculosis


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Active Site Loop Dynamics of A Class Iia Fructose 1,6-Bisphosphate Aldolase From M. Tuberculosis within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn402

b:27.5
occ:1.00
ND1 A:HIS344 1.9 23.4 1.0
NE2 A:HIS346 2.2 37.3 1.0
O A:HOH600 2.3 29.9 1.0
CE1 A:HIS344 2.8 24.5 1.0
CG A:HIS344 3.0 23.7 1.0
CE1 A:HIS346 3.1 37.9 1.0
CD2 A:HIS346 3.1 39.8 1.0
CB A:HIS344 3.5 26.3 1.0
O A:HOH578 3.8 26.3 1.0
NE2 A:HIS344 4.0 24.7 1.0
CA A:HIS344 4.0 28.2 1.0
CD2 A:HIS344 4.1 24.4 1.0
ND1 A:HIS346 4.2 39.2 1.0
CG A:HIS346 4.3 40.9 1.0
C A:HIS344 4.9 32.2 1.0
O A:HIS344 4.9 33.7 1.0

Reference:

S.D.Pegan, K.Rukseree, G.C.Capodagli, E.A.Baker, O.Krasnykh, S.G.Franzblau, A.D.Mesecar. Active Site Loop Dynamics of A Class Iia Fructose 1,6-Bisphosphate Aldolase From Mycobacterium Tuberculosis. Biochemistry V. 52 912 2013.
ISSN: ISSN 0006-2960
PubMed: 23298222
DOI: 10.1021/BI300928U
Page generated: Wed Dec 16 05:11:00 2020

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy