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Atomistry » Zinc » PDB 4cxv-4d7v » 4d3b » |
Zinc in PDB 4d3b: Structure of Rat Neuronal Nitric Oxide Synthase Heme Domain in Complex with N1-(2-(1H-Imidazol-1-Yl)Pyrimidin-4-Yl)-N2- (3-Fluorophenethyl)Ethane-1,2-DiamineEnzymatic activity of Structure of Rat Neuronal Nitric Oxide Synthase Heme Domain in Complex with N1-(2-(1H-Imidazol-1-Yl)Pyrimidin-4-Yl)-N2- (3-Fluorophenethyl)Ethane-1,2-Diamine
All present enzymatic activity of Structure of Rat Neuronal Nitric Oxide Synthase Heme Domain in Complex with N1-(2-(1H-Imidazol-1-Yl)Pyrimidin-4-Yl)-N2- (3-Fluorophenethyl)Ethane-1,2-Diamine:
1.14.13.39; Protein crystallography data
The structure of Structure of Rat Neuronal Nitric Oxide Synthase Heme Domain in Complex with N1-(2-(1H-Imidazol-1-Yl)Pyrimidin-4-Yl)-N2- (3-Fluorophenethyl)Ethane-1,2-Diamine, PDB code: 4d3b
was solved by
H.Li,
T.L.Poulos,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4d3b:
The structure of Structure of Rat Neuronal Nitric Oxide Synthase Heme Domain in Complex with N1-(2-(1H-Imidazol-1-Yl)Pyrimidin-4-Yl)-N2- (3-Fluorophenethyl)Ethane-1,2-Diamine also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Structure of Rat Neuronal Nitric Oxide Synthase Heme Domain in Complex with N1-(2-(1H-Imidazol-1-Yl)Pyrimidin-4-Yl)-N2- (3-Fluorophenethyl)Ethane-1,2-Diamine
(pdb code 4d3b). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Structure of Rat Neuronal Nitric Oxide Synthase Heme Domain in Complex with N1-(2-(1H-Imidazol-1-Yl)Pyrimidin-4-Yl)-N2- (3-Fluorophenethyl)Ethane-1,2-Diamine, PDB code: 4d3b: Zinc binding site 1 out of 1 in 4d3bGo back to Zinc Binding Sites List in 4d3b
Zinc binding site 1 out
of 1 in the Structure of Rat Neuronal Nitric Oxide Synthase Heme Domain in Complex with N1-(2-(1H-Imidazol-1-Yl)Pyrimidin-4-Yl)-N2- (3-Fluorophenethyl)Ethane-1,2-Diamine
Mono view Stereo pair view
Reference:
P.Mukherjee,
H.Li,
I.F.Sevrioukova,
G.Chreifi,
P.Martasek,
L.J.Roman,
T.L.Poulos,
R.B.Silverman.
Novel 2,4-Disubstituted Pyrimidines As Potent, Selective, and Cell-Permeable Inhibitors of Neuronal Nitric Oxide Synthase. J.Med.Chem. 2014.
Page generated: Sat Oct 26 21:19:35 2024
ISSN: ESSN 1520-4804 PubMed: 25489882 DOI: 10.1021/JM501719E |
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