Zinc in PDB 4d1u: A D120A Mutant of Vim-7 From Pseudomonas Aeruginosa

The structure of A D120A Mutant of Vim-7 From Pseudomonas Aeruginosa, PDB code: 4d1u was solved by H.-K.S.Leiros, S.Skagseth, K.S.W.Edvardsen, M.S.Lorentzen, G.E.K.Bjerga, I.Leiros, O.Samuelsen, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	24.665 / 1.80
Space group	P 43
Cell size a, b, c (Å), α, β, γ (°)	69.764, 69.764, 47.286, 90.00, 90.00, 90.00
R / Rfree (%)	16.06 / 20.75

The binding sites of Zinc atom in the A D120A Mutant of Vim-7 From Pseudomonas Aeruginosa (pdb code 4d1u). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the A D120A Mutant of Vim-7 From Pseudomonas Aeruginosa, PDB code: 4d1u:

Zinc binding site 1 out of 1 in the A D120A Mutant of Vim-7 From Pseudomonas Aeruginosa


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of A D120A Mutant of Vim-7 From Pseudomonas Aeruginosa within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1292 b:13.1 occ:1.00 ND1 A:HIS118 2.0 14.2 1.0 O A:HOH2074 2.0 19.3 1.0 NE2 A:HIS196 2.0 12.3 1.0 NE2 A:HIS116 2.1 9.7 1.0 O A:HOH2075 2.3 16.4 1.0 CE1 A:HIS118 2.9 16.6 1.0 CE1 A:HIS196 3.0 21.0 1.0 CE1 A:HIS116 3.0 16.8 1.0 HB2 A:HIS118 3.0 14.6 1.0 CG A:HIS118 3.1 18.9 1.0 HE1 A:HIS118 3.1 19.9 1.0 CD2 A:HIS196 3.1 13.1 1.0 HE1 A:HIS116 3.1 20.1 1.0 HE1 A:HIS196 3.2 25.2 1.0 CD2 A:HIS116 3.2 12.7 1.0 HD2 A:HIS196 3.3 15.7 1.0 HD2 A:HIS116 3.4 15.2 1.0 CB A:HIS118 3.5 12.2 1.0 HB3 A:HIS118 3.7 14.6 1.0 O A:HOH2147 4.0 18.2 1.0 NE2 A:HIS118 4.1 17.9 1.0 ND1 A:HIS196 4.1 12.0 1.0 ND1 A:HIS116 4.1 11.5 1.0 CD2 A:HIS118 4.2 14.9 1.0 HB2 A:CYS221 4.2 18.1 1.0 CG A:HIS196 4.2 9.3 1.0 CG A:HIS116 4.2 8.6 1.0 O A:HOH2146 4.4 31.6 1.0 O A:HOH2044 4.4 33.0 1.0 HB1 A:ALA120 4.4 27.7 1.0 HB3 A:CYS221 4.4 18.1 1.0 SG A:CYS221 4.5 16.7 1.0 O A:HOH2126 4.5 31.0 1.0 CB A:CYS221 4.6 15.1 1.0 H A:HIS118 4.6 11.4 1.0 HE2 A:HIS118 4.8 21.5 1.0 HB3 A:SER197 4.9 20.5 1.0 HD1 A:HIS196 4.9 14.4 1.0 CA A:HIS118 4.9 9.3 1.0 HD1 A:HIS116 4.9 13.8 1.0 HG2 A:ARG121 5.0 19.2 1.0 HD21 A:ASN233 5.0 53.4 1.0 HB3 A:ASN233 5.0 44.0 1.0

H.-K.S.Leiros, S.Skagseth, K.S.W.Edvardsen, M.S.Lorentzen, G.E.K.Bjerga, I.Leiros, O.Samuelsen. HIS224 Alters the R2 Drug Binding Site and PHE218 Influences the Catalytic Efficiency in the Metallo-Beta-Lactamase Vim-7. Antimicrob.Agents Chemother. V. 58 4826 2014.
ISSN: ISSN 0066-4804
PubMed: 24913158
DOI: 10.1128/AAC.02735-13